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种族对帕金森病非运动症状的影响。

Impact of ethnicity on non-motor symptoms of Parkinson's disease.

机构信息

Parkinson's Clinic of Eastern Toronto and Movement Disorders Centre, Broadview Ave, Toronto, ON, Canada.

出版信息

J Parkinsons Dis. 2012;2(4):281-5. doi: 10.3233/JPD-129002.

Abstract

Parkinson's disease (PD) is a neurodegenerative illness characterized by various non-motor symptoms that may contribute to disability, impaired quality of life and shortened life expectancy. The aim of present study was to determine the relative prevalence of common non-motor symptoms in various ethnic groups. A retrospective chart analysis was performed on Parkinson's disease patients where a total of 314 PD patients from six ethnic categories were examined for the occurrence of anxiety, visual hallucinations, nocturia, drooling and dementia. Our results show that anxiety in PD patients was correlated with their ethnicity classification. Interesting trends were observed with respect to nocturia and dementia symptoms and no significant differences were found between ethnic groups for visual hallucinations and drooling. Our study shows that non-motor symptoms of Parkinson's disease are prevalent across all ethnic groups, and except anxiety there may not be any impact of ethnicity on dementia, nocturia, drooling, and visual hallucinations.

摘要

帕金森病(PD)是一种神经退行性疾病,其特征是存在各种非运动症状,这些症状可能导致残疾、生活质量受损和预期寿命缩短。本研究的目的是确定不同种族人群常见非运动症状的相对患病率。对帕金森病患者进行了回顾性图表分析,共检查了来自六个种族类别的 314 名 PD 患者,以确定焦虑、视觉幻觉、夜尿症、流涎和痴呆的发生情况。我们的结果表明,PD 患者的焦虑与他们的种族分类有关。有趣的是,我们观察到夜尿症和痴呆症状的趋势,并且在视觉幻觉和流涎方面,不同种族之间没有发现显著差异。我们的研究表明,帕金森病的非运动症状在所有种族中都很普遍,除了焦虑之外,种族对痴呆、夜尿症、流涎和视觉幻觉没有任何影响。

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