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不同种族帕金森病患者夜尿症的患病率。

Prevalence of nocturia in Parkinson's disease patients from various ethnicities.

作者信息

Rana Abdul Qayyum, Vaid Haris, Akhter Mohammad Raza, Awan Naeem Yousaf, Fattah Abdul, Cader Muhammad Husain, Hafez Kevin, Rana Mohammad Abdullah, Yousuf Muhammad Saad

出版信息

Neurol Res. 2014 Mar;36(3):234-8. doi: 10.1179/1743132813Y.0000000264. Epub 2013 Dec 6.

Abstract

OBJECTIVES

One of the most common non-motor symptoms in Parkinson's disease (PD) is nocturia. This paper seeks to address the prevalence of nocturia in PD and correlate it to various factors such as gender, Hoehn and Yahr (H&Y) stage, age, and ethnicities.

METHODS

In particular, 332 PD patients were seen in a community movement disorders clinic and their charts were analyzed from 2005 to 2010. Within this population, more than one-third (34.9%) patients were diagnosed with nocturia.

RESULTS

Age, gender, and PD stage were significant predictors of nocturia in PD. With every one-year increase in age, the odds of developing nocturia in PD increases by 3.1% while an increase in H&Y stage increases the odds of nocturia in PD by 1.645 times. Also, males had greater odds of experiencing nocturia in PD. Ethnicities alone were of no significant importance. However, after performing interaction analyses, Asian and Indian males, especially, were at significantly greater risk than other ethnicities.

DISCUSSION

Future research is indeed required to understand why certain ethnicities are especially at risk. Clinicians must also be aware of the epidemiology of nocturia in PD to prevent and treat this debilitating symptom.

摘要

目的

帕金森病(PD)最常见的非运动症状之一是夜尿症。本文旨在探讨PD患者夜尿症的患病率,并将其与性别、霍恩和雅尔(H&Y)分期、年龄及种族等各种因素相关联。

方法

具体而言,在一家社区运动障碍诊所对332例PD患者进行了观察,并分析了他们2005年至2010年的病历。在该人群中,超过三分之一(34.9%)的患者被诊断为夜尿症。

结果

年龄、性别和PD分期是PD患者夜尿症的重要预测因素。年龄每增加一岁,PD患者出现夜尿症的几率增加3.1%,而H&Y分期的增加使PD患者夜尿症的几率增加1.645倍。此外,男性PD患者出现夜尿症的几率更高。种族本身并不具有显著意义。然而,在进行交互分析后,尤其是亚洲和印度男性,比其他种族面临的风险显著更高。

讨论

确实需要未来的研究来了解为什么某些种族尤其面临风险。临床医生也必须了解PD患者夜尿症的流行病学情况,以预防和治疗这种使人衰弱的症状。

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