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成功治疗溃疡性结肠炎相关的脑静脉血栓形成。

Successful treatment of cerebral venous thrombosis associated with ulcerative colitis.

机构信息

Division of Neurology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan.

出版信息

J Stroke Cerebrovasc Dis. 2013 Nov;22(8):e684-6. doi: 10.1016/j.jstrokecerebrovasdis.2013.07.023. Epub 2013 Aug 9.

Abstract

Thromboembolic complications, such as deep venous thrombosis and pulmonary embolism, are well described in patients with inflammatory bowel disease, but cerebral venous thrombosis (CVT) is a rare but potentially devastating complication. The authors describe the case of a 36-year-old Japanese man presenting with CVT associated with ulcerative colitis (UC) that was successfully treated with a combination of continuous anticoagulant and pulse steroid therapy. Our observations suggest that aggressive therapy for inducing acute UC remission is vitally important for CVT associated with UC.

摘要

血栓栓塞并发症,如深静脉血栓形成和肺栓塞,在炎症性肠病患者中已有很好的描述,但脑静脉血栓形成(CVT)是一种罕见但潜在破坏性的并发症。作者描述了一例 36 岁的日本男性,患有与溃疡性结肠炎(UC)相关的 CVT,联合使用连续抗凝和脉冲类固醇治疗后成功治愈。我们的观察表明,积极诱导急性 UC 缓解的治疗对于与 UC 相关的 CVT 至关重要。

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