Krcméry V
Výskumný ústav preventívneho lekárstva, Bratislava.
Cas Lek Cesk. 1990 Jul 20;129(29):914-6.
The author submits information on the preparation and properties of new molecules of "tailored antibiotics"--dual cephalosporins. They are formed by esterification of cephalosporins of the third generation (so far only cephotaxim) with fleroxacine or another fluoroquinolone chemotherapeutic agent. The author discusses the aptness and advantage of this new approach to the innovation of the existing spectrum of antibacterial agents.
作者提交了关于“定制抗生素”——双头孢菌素新型分子的制备及特性的信息。它们是通过第三代头孢菌素(目前仅头孢噻肟)与氟罗沙星或另一种氟喹诺酮类化疗药物酯化而成。作者讨论了这种创新现有抗菌谱新方法的适用性和优势。