Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China.
Chem Commun (Camb). 2013 Sep 25;49(74):8190-2. doi: 10.1039/c3cc44914a.
An unprecedented alkylation reaction of malononitriles with enantioenriched primary allylic amines has been developed in a stereospecific manner through palladium-catalyzed sp(3) C-N bond cleavage without additives at room temperature.
发展了一种通过钯催化 sp(3) C-N 键断裂，在室温无添加剂条件下，以立体专一的方式实现丙二腈与手性富集的一级烯丙基胺的前所未有的烷基化反应。
