天然弗赖登烷。

Natural friedelanes.

机构信息

College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, P. R. China.

出版信息

Chem Biodivers. 2013 Aug;10(8):1392-434. doi: 10.1002/cbdv.201100256.

DOI:10.1002/cbdv.201100256

Abstract

This review covers the occurrence and biological activities of all natural friedelane triterpenoids found between 1977 and March 2011. The biogeneses of dimeric friedelanes and several rearranged friedelanes are discussed. The pharmacological properties of representative compounds, including celastrol and correolide, have also been compiled, on the basis of 344 references.

摘要

本综述涵盖了 1977 年至 2011 年 3 月期间发现的所有天然的弗里德尔烷型三萜的分布和生物活性。讨论了二聚弗里德尔烷和一些重排的弗里德尔烷的生源途径。根据 344 篇参考文献，综述了代表性化合物（包括雷公藤红素和考雷醇内酯）的药理学性质。