五环三萜类化合物从卫矛科植物中分离出来：C-NMR 数据的焦点。
Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the C-NMR Data.
机构信息
Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Avenida Presidente Antônio Carlos, 6627, Pampulha, Belo Horizonte 31270-901, MG, Brazil.
出版信息
Molecules. 2022 Jan 31;27(3):959. doi: 10.3390/molecules27030959.
The Celastraceae family comprises about 96 genera and more than 1.350 species, occurring mainly in tropical and subtropical regions of the world. The species of this family stand out as important plant sources of triterpenes, both in terms of abundance and structural diversity. Triterpenoids found in Celastraceae species display mainly lupane, ursane, oleanane, and friedelane skeletons, exhibiting a wide range of biological activities such as antiviral, antimicrobial, analgesic, anti-inflammatory, and cytotoxic against various tumor cell lines. This review aimed to document all triterpenes isolated from different botanical parts of species of the Celastraceae family covering 2001 to 2021. Furthermore, a compilation of their C-NMR data was carried out to help characterize compounds in future investigations. A total of 504 pentacyclic triterpenes were compiled and distinguished as 29 aromatic, 50 dimers, 103 friedelanes, 89 lupanes, 102 oleananes, 22 quinonemethides, 88 ursanes and 21 classified as others.
卫矛科包含约 96 属和 1350 余种，主要分布于世界热带和亚热带地区。该科的物种是三萜类化合物的重要植物来源，无论是在丰度还是结构多样性方面都很突出。在卫矛科物种中发现的三萜类化合物主要具有羽扇豆烷型、乌苏烷型、齐墩果烷型和呋甾烷型骨架，具有广泛的生物活性，如抗病毒、抗菌、镇痛、抗炎和对各种肿瘤细胞系的细胞毒性。本综述旨在记录 2001 年至 2021 年间从卫矛科不同植物部位分离得到的所有三萜类化合物。此外，还对其 C-NMR 数据进行了汇编，以帮助在未来的研究中对化合物进行表征。共编译了 504 种五环三萜类化合物，分为 29 种芳香族、50 种二聚体、103 种呋甾烷型、89 种羽扇豆烷型、102 种齐墩果烷型、22 种醌甲基化物、88 种乌苏烷型和 21 种其他类型。
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