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用于识别严重创伤性脑损伤的替代分诊规则的准确性:一项诊断队列研究。

The accuracy of alternative triage rules for identification of significant traumatic brain injury: a diagnostic cohort study.

作者信息

Fuller Gordon, Lawrence Thomas, Woodford Maralyn, Lecky Fiona

机构信息

Trauma Audit and Research Network, Health Sciences Research Group, Manchester Academic Health Sciences Centre, Salford Royal Hospital, Salford, UK.

School of Health and Related Research, University of Sheffield, Sheffield, UK.

出版信息

Emerg Med J. 2014 Nov;31(11):914-9. doi: 10.1136/emermed-2013-202575. Epub 2013 Aug 12.

Abstract

INTRODUCTION

Traumatic brain injury (TBI) is a leading cause of death and disability in young adults. Reorganisation of trauma services with direct triage of suspected head injury patients to trauma centres may improve outcomes following TBI. This study aimed to determine the sensitivity of principal English triage tools for identifying significant TBI.

METHODS

We performed a diagnostic cohort study using data prospectively collated from the Trauma Audit and Research Network database between 2005 and 2011. Adult head injury patients were retrospectively classified according to London Ambulance Service (LAS) and Head Injury Transportation Straight to Neurosurgery study (HITS-NS) triage criteria. Sensitivity and specificity were then calculated against a reference standard of significant TBI, comprising head region abbreviated injury score (AIS) ≥3 or neurosurgical operation.

RESULTS

6559 patients were included in complete case analyses. The LAS and HITS-NS triage tools demonstrated sensitivities of 44.5% (95% CI 43.2 to 45.9) and 32.6% (95% CI 31.4 to 33.9), respectively, for identifying significant TBI patients. False negative significant TBI cases were relatively older, more likely to be female, more frequently secondary to low-level falls, and were less likely to have very severe AIS five or six head injuries, p<0.01.

CONCLUSIONS

A considerable proportion of significant head injury patients may not be triaged directly to trauma centres. Investment is therefore necessary to improve the accuracy of existing triage rules and maintain expertise in TBI diagnosis and management in non-specialist emergency departments.

摘要

引言

创伤性脑损伤(TBI)是导致年轻成年人死亡和残疾的主要原因。对创伤服务进行重组,将疑似头部受伤患者直接分诊至创伤中心,可能会改善TBI后的治疗效果。本研究旨在确定主要英文分诊工具识别严重TBI的敏感性。

方法

我们进行了一项诊断队列研究,使用了2005年至2011年间从创伤审计与研究网络数据库前瞻性收集的数据。成年头部受伤患者根据伦敦救护车服务(LAS)和直接送往神经外科的头部损伤运输研究(HITS-NS)分诊标准进行回顾性分类。然后根据严重TBI的参考标准计算敏感性和特异性,该标准包括头部区域简明损伤评分(AIS)≥3或进行神经外科手术。

结果

6559例患者纳入完整病例分析。LAS和HITS-NS分诊工具识别严重TBI患者的敏感性分别为44.5%(95%CI 43.2至45.9)和32.6%(95%CI 31.4至33.9)。假阴性严重TBI病例年龄相对较大,女性更常见,更多继发于低级别跌倒,且发生AIS 5或6级非常严重头部损伤的可能性较小,p<0.01。

结论

相当一部分严重头部受伤患者可能无法直接分诊至创伤中心。因此,有必要进行投入,以提高现有分诊规则的准确性,并在非专科急诊科维持TBI诊断和管理方面的专业知识。

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