Prochazka Antonin, Korpas David
Institute of Biophysics and Informatics, 1st Medical Faculty, Charles University, Prague;
Exp Clin Cardiol. 2013 Spring;18(2):85-8.
To evaluate whether pacing or sensing configuration has an effect on pacing parameters or their time progression. Three left ventricular (LV) pacing parameters were monitored - the LV pacing threshold, pacing impedance and intrinsic R-wave amplitude.
DATA WERE COLLECTED AT THREE INTERVALS: during implantation; between the second and fifth month after implantation (first follow-up); and between the eighth and 15th month after implantation (second follow-up). Repeated-measures ANOVA was used for the statistical analysis.
The impedance, but not its time progression, was significantly higher for the LV tip to LV ring configuration than for other configurations. R-wave amplitude and impedance increased significantly (without dependance on configurations) between implantation and first follow-up, as expected. The time progression of any parameter was not dependent on configuration of the LV lead.
LV tip to LV ring is the best configuration for maintaining a high impedance level. It is better to maintain an individual approach for pacing threshold and R-wave amplitude, and their settings.
评估起搏或感知配置是否对起搏参数或其时间进程有影响。监测了三个左心室（LV）起搏参数——左心室起搏阈值、起搏阻抗和固有R波振幅。
在三个时间段收集数据：植入期间；植入后第二个月至第五个月之间（首次随访）；以及植入后第八个月至第十五个月之间（第二次随访）。采用重复测量方差分析进行统计分析。
左心室尖端至左心室环配置的阻抗显著高于其他配置，但其时间进程并非如此。正如预期的那样，在植入和首次随访之间，R波振幅和阻抗显著增加（与配置无关）。任何参数的时间进程均不依赖于左心室导线的配置。
左心室尖端至左心室环是维持高阻抗水平的最佳配置。对于起搏阈值和R波振幅及其设置，最好采用个体化方法。
