Vichova Teodora, Motovska Zuzana
Third Medical Faculty of Charles University and University Hospital Royal Vineyards, Prague, Czech Republic.
Exp Clin Cardiol. 2013 Spring;18(2):e88-91.
The role of oxidative stress in cardiovascular disease processes, such as atherogenesis, ischemic-reperfusion injury and cardiac remodelling, has been increasingly recognized in the past few decades. Currently, an increasing number of studies suggest that levels of oxidative stress markers in body fluids correlate with atherosclerotic disease activity. This finding may lead to novel clinical approaches in patients with coronary artery disease. Assessment of oxidative stress markers could modify risk stratification and treatment of patients with suspected coronary artery disease or myocardial infarction.
在过去几十年里,氧化应激在心血管疾病进程(如动脉粥样硬化、缺血再灌注损伤和心脏重塑)中的作用已得到越来越多的认可。目前,越来越多的研究表明,体液中氧化应激标志物的水平与动脉粥样硬化疾病活动相关。这一发现可能会为冠心病患者带来新的临床治疗方法。对氧化应激标志物的评估可能会改变疑似冠心病或心肌梗死患者的风险分层和治疗方案。