• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

氧化应激:冠状动脉疾病的预测标志物。

Oxidative stress: Predictive marker for coronary artery disease.

作者信息

Vichova Teodora, Motovska Zuzana

机构信息

Third Medical Faculty of Charles University and University Hospital Royal Vineyards, Prague, Czech Republic.

出版信息

Exp Clin Cardiol. 2013 Spring;18(2):e88-91.

PMID:23940453
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3718605/
Abstract

The role of oxidative stress in cardiovascular disease processes, such as atherogenesis, ischemic-reperfusion injury and cardiac remodelling, has been increasingly recognized in the past few decades. Currently, an increasing number of studies suggest that levels of oxidative stress markers in body fluids correlate with atherosclerotic disease activity. This finding may lead to novel clinical approaches in patients with coronary artery disease. Assessment of oxidative stress markers could modify risk stratification and treatment of patients with suspected coronary artery disease or myocardial infarction.

摘要

在过去几十年里,氧化应激在心血管疾病进程(如动脉粥样硬化、缺血再灌注损伤和心脏重塑)中的作用已得到越来越多的认可。目前,越来越多的研究表明,体液中氧化应激标志物的水平与动脉粥样硬化疾病活动相关。这一发现可能会为冠心病患者带来新的临床治疗方法。对氧化应激标志物的评估可能会改变疑似冠心病或心肌梗死患者的风险分层和治疗方案。

相似文献

1
Oxidative stress: Predictive marker for coronary artery disease.氧化应激:冠状动脉疾病的预测标志物。
Exp Clin Cardiol. 2013 Spring;18(2):e88-91.
2
Relationship between oxidative stress, lipid peroxidation, and ultrastructural damage in patients with coronary artery disease undergoing cardioplegic arrest/reperfusion.接受心脏停搏/再灌注的冠心病患者氧化应激、脂质过氧化与超微结构损伤之间的关系
Cardiovasc Res. 2007 Mar 1;73(4):710-9. doi: 10.1016/j.cardiores.2006.12.007. Epub 2006 Dec 12.
3
Hypertrophied myocardium is vulnerable to ischemia/reperfusion injury and refractory to rapamycin-induced protection due to increased oxidative/nitrative stress.肥厚的心肌容易受到缺血/再灌注损伤的影响,并且由于氧化/硝化应激增加,对雷帕霉素诱导的保护作用具有抗性。
Clin Sci (Lond). 2018 Jan 11;132(1):93-110. doi: 10.1042/CS20171471. Print 2018 Jan 16.
4
Effect of N-acetylcysteine in attenuating ischemic reperfusion injury in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass.N-乙酰半胱氨酸对接受体外循环冠状动脉搭桥术患者减轻缺血再灌注损伤的作用。
Ann Vasc Surg. 2009 Sep-Oct;23(5):645-51. doi: 10.1016/j.avsg.2008.12.005. Epub 2009 May 21.
5
Adipocytokine resistin correlates with oxidative stress and myocardial injury in patients undergoing cardiac surgery.脂肪细胞因子抵抗素与心脏手术患者的氧化应激和心肌损伤相关。
Eur J Cardiothorac Surg. 2014 Oct;46(4):729-36. doi: 10.1093/ejcts/ezt634. Epub 2014 Jan 30.
6
API expert consensus document on management of ischemic heart disease.缺血性心脏病管理的API专家共识文件
J Assoc Physicians India. 2006 Jun;54:469-80.
7
Demonstration of ischemia-reperfusion injury separate from postoperative infarction in coronary artery bypass graft patients.冠状动脉搭桥术患者中缺血再灌注损伤与术后梗死相分离的证明。
Ann Thorac Surg. 1998 Jan;65(1):48-53. doi: 10.1016/s0003-4975(97)01036-9.
8
[Diagnostic and prognostic value of atherosclerosis risk factors for predicting 1 year outcome in patients with acute myocardial infarction and in patients with stable coronary artery disease receiving percutaneous transluminal coronary angioplasty].[动脉粥样硬化危险因素对预测急性心肌梗死患者及接受经皮腔内冠状动脉成形术的稳定冠状动脉疾病患者1年预后的诊断和预后价值]
Folia Med Cracov. 2009;50(3-4):43-54.
9
Myocardial ischemia-reperfusion injury, antioxidant enzyme systems, and selenium: a review.心肌缺血-再灌注损伤、抗氧化酶系统与硒:综述
Curr Med Chem. 2007;14(14):1539-49. doi: 10.2174/092986707780831078.
10
Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning.心血管危险因素与心肌缺血/再灌注损伤、预处理及后处理之间的相互作用。
Pharmacol Rev. 2007 Dec;59(4):418-58. doi: 10.1124/pr.107.06002. Epub 2007 Nov 29.

引用本文的文献

1
The Role of Circulating Biomarkers in Patients with Coronary Microvascular Disease.循环生物标志物在冠状动脉微血管疾病患者中的作用
Biomolecules. 2025 Jan 25;15(2):177. doi: 10.3390/biom15020177.
2
Fetal adnexa-derived allogeneic mesenchymal stem cells for cardiac regeneration: the future trend of cell-based therapy for age-related adverse conditions.用于心脏再生的胎儿附件来源的同种异体间充质干细胞:基于细胞治疗年龄相关不良状况的未来趋势。
Hum Cell. 2025 Feb 25;38(2):61. doi: 10.1007/s13577-025-01190-2.
3
Exploring Novel Biomarkers for an Acute Coronary Syndrome Diagnosis Utilizing Plasma Metabolomics.利用血浆代谢组学探索急性冠状动脉综合征诊断的新型生物标志物。
Int J Mol Sci. 2024 Jun 18;25(12):6674. doi: 10.3390/ijms25126674.
4
Albumin Redox Modifications Promote Cell Calcification Reflecting the Impact of Oxidative Status on Aortic Valve Disease and Atherosclerosis.白蛋白氧化还原修饰促进细胞钙化,反映氧化状态对主动脉瓣疾病和动脉粥样硬化的影响。
Antioxidants (Basel). 2024 Jan 16;13(1):108. doi: 10.3390/antiox13010108.
5
Association of Coronary Stenosis With Cerebral Small Vessel Diseases in Neurologically Asymptomatic Adults.神经无症状成年人冠状动脉狭窄与脑小血管疾病的关联
J Stroke. 2024 Jan;26(1):104-107. doi: 10.5853/jos.2023.01732. Epub 2024 Jan 22.
6
Structural Characteristics of PON1 with Leu55Met and Gln192Arg Variants Influencing Oxidative-Stress-Related Diseases: An Integrated Molecular Modeling and Dynamics Study.PON1 基因 Leu55Met 和 Gln192Arg 变异影响氧化应激相关疾病的结构特征:综合分子建模和动力学研究。
Medicina (Kaunas). 2023 Nov 22;59(12):2060. doi: 10.3390/medicina59122060.
7
Effect of temperature fluctuations in cold seasons on acute myocardial infarction hospitalisations in northeast China: a retrospective observational cohort study.寒冷季节温度波动对中国东北地区急性心肌梗死住院的影响:一项回顾性观察性队列研究。
BMJ Open. 2023 Nov 29;13(11):e073528. doi: 10.1136/bmjopen-2023-073528.
8
High density lipoprotein heterogeneity & function among Indians with coronary artery disease.冠心病印度患者的高密度脂蛋白异质性与功能
Indian J Med Res. 2023 Sep;158(3):292-302. doi: 10.4103/ijmr.ijmr_1212_22.
9
Homo-oxidized HSPB1 protects H9c2 cells against oxidative stress via activation of KEAP1/NRF2 signaling pathway.同源氧化的热休克蛋白B1(HSPB1)通过激活KEAP1/NRF2信号通路保护H9c2细胞免受氧化应激。
iScience. 2023 Jul 20;26(8):107443. doi: 10.1016/j.isci.2023.107443. eCollection 2023 Aug 18.
10
The Role of Systemic Oxidative Status in Coronary Arterial and Peripheral Venous Blood of Patients with Unstable Angina Pectoris.全身氧化状态在不稳定型心绞痛患者冠状动脉血和外周静脉血中的作用
Life (Basel). 2023 Jul 11;13(7):1537. doi: 10.3390/life13071537.

本文引用的文献

1
Platelet activation, oxidative stress and overexpression of inducible nitric oxide synthase in moderate heart failure.血小板活化、氧化应激与诱导型一氧化氮合酶在中度心力衰竭中的过度表达。
Clin Exp Pharmacol Physiol. 2011 Oct;38(10):705-10. doi: 10.1111/j.1440-1681.2011.05580.x.
2
Prolonged pain to hospital time is associated with increased plasma advanced oxidation protein products and poor prognosis in patients with percutaneous coronary intervention for ST-elevation myocardial infarction.对于ST段抬高型心肌梗死接受经皮冠状动脉介入治疗的患者,从疼痛发作到入院的时间延长与血浆晚期氧化蛋白产物增加及预后不良相关。
Heart Vessels. 2010 Sep;25(5):374-8. doi: 10.1007/s00380-009-1220-8. Epub 2010 Jul 31.
3
Oxidized LDL in human carotid plaques is related to symptomatic carotid disease and lesion instability.人颈动脉斑块中的氧化型 LDL 与有症状的颈动脉疾病和斑块不稳定有关。
J Vasc Surg. 2010 Sep;52(3):704-13. doi: 10.1016/j.jvs.2010.03.047. Epub 2010 Jun 22.
4
Oxidative stress and ischemic myocardial syndromes.氧化应激与缺血性心肌综合征。
Med Sci Monit. 2009 Oct;15(10):RA209-219.
5
No-reflow phenomenon in patients with acute myocardial infarction: its pathophysiology and clinical implications.急性心肌梗死患者的无复流现象:其病理生理学及临床意义
Acta Med Okayama. 2009 Aug;63(4):161-8. doi: 10.18926/AMO/31817.
6
Myocardial repair/remodelling following infarction: roles of local factors.心肌梗死后的心肌修复/重塑:局部因素的作用
Cardiovasc Res. 2009 Feb 15;81(3):482-90. doi: 10.1093/cvr/cvn333. Epub 2008 Dec 2.
7
Oxidative stress and left ventricular remodelling after myocardial infarction.心肌梗死后的氧化应激与左心室重构
Cardiovasc Res. 2009 Feb 15;81(3):457-64. doi: 10.1093/cvr/cvn335. Epub 2008 Dec 1.
8
Relationship between coronary plaque formation and NAD(P)H oxidase-derived reactive oxygen species - comparison of intravascular ultrasound finding of atherosclerotic lesions with histochemical characteristics-.
Kobe J Med Sci. 2007;53(3):107-17.
9
The role of oxidants and free radicals in reperfusion injury.氧化剂和自由基在再灌注损伤中的作用。
Cardiovasc Res. 2006 May 1;70(2):181-90. doi: 10.1016/j.cardiores.2006.02.025. Epub 2006 Mar 3.
10
Persistent high levels of plasma oxidized low-density lipoprotein after acute myocardial infarction predict stent restenosis.急性心肌梗死后血浆氧化型低密度脂蛋白持续高水平可预测支架再狭窄。
Arterioscler Thromb Vasc Biol. 2006 Apr;26(4):877-83. doi: 10.1161/01.ATV.0000209886.31510.7f. Epub 2006 Feb 9.