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孕妇对胎儿染色体异常产前筛查的知识与态度:克罗地亚多中心调查

Pregnant women's knowledge and attitudes to prenatal screening for fetal chromosomal abnormalities: Croatian multicentric survey.

作者信息

Kosec Vesna, Zec Ivana, Tislarić-Medenjak Dubravka, Kuna Krunoslav, Simundić Ana Maria, Lajtman-Krizaić Marta, Lovrić Boris, Mimica Marko, Estatiev Zrinka Komadina, Borgudan Vesna

机构信息

University of Zagreb, University Hospital Center "Sestre milosrdnice", Clinic for Gynecology and Obstetrics, Zagreb, Croatia.

出版信息

Coll Antropol. 2013 Jun;37(2):483-9.

PMID:23940994
Abstract

We aimed to assess opinion and preferences of Croatian pregnant women regarding the prenatal screening tests for trisomies. The study was conducted in Zagreb, Split, Cakovec, Nova Gradiska, Gospić and Zlatar. It was organized in the public primary healthcare centers, among the pregnant volunteers during their first visit to an antenatal clinic (7-12 weeks pregnant). The respondents filled anonymous questionnaire reflecting their knowledge and attitudes to the screening options. In total, 437 completed questionnaires were selected. The average maternal age and the level of education differed significantly between the respondents in the respective cities (P < 0.001). Of the respondents with positive attitude towards screening, the majority would prefer the first-trimester combined test (160/219; 73.1%), while 37/219 (16.9%) opted for the second-trimester biochemical screening. The remaining 22/219 (10.0%) would accept only the ultrasound screening. Among the 224 respondents, who would accept the combined first-trimester test, 95 (42.4%) held a college and university degree, whereas among 59 women, who would choose the second-trimester biochemical screening, 14 were highly educated (23.7%). The difference was statistically significant (P = 0.016). The univariate regression analysis showed that age, level of education and previous information were significant variables predictive for the choice of the test; the level of education and previous knowledge remained significant in the multivariate model. The survey has revealed some of the points that should be improved in the future concept of screening program in Croatia. Health professionals should persist to mend women's knowledge about prenatal screening, taking into consideration women's preferences as well.

摘要

我们旨在评估克罗地亚孕妇对三体综合征产前筛查测试的看法和偏好。该研究在萨格勒布、斯普利特、察科韦茨、新格拉迪什卡、戈斯皮奇和兹拉塔尔进行。研究在公共初级医疗保健中心开展,对象为首次前往产前诊所就诊(怀孕7至12周)的孕妇志愿者。受访者填写了反映她们对筛查选项的了解和态度的匿名问卷。总共选取了437份完整问卷。各城市受访者的平均产妇年龄和教育水平差异显著(P < 0.001)。在对筛查持积极态度的受访者中,大多数人更喜欢孕早期联合检测(160/219;73.1%),而37/219(16.9%)的人选择了孕中期生化筛查。其余22/219(10.0%)的人只接受超声筛查。在224名愿意接受孕早期联合检测的受访者中,95人(42.4%)拥有大专及本科学历,而在59名选择孕中期生化筛查的女性中,14人受过高等教育(23.7%)。差异具有统计学意义(P = 0.016)。单因素回归分析表明,年龄、教育水平和先前信息是预测检测选择的重要变量;在多变量模型中,教育水平和先前知识仍然具有显著性。该调查揭示了克罗地亚未来筛查计划概念中应改进的一些要点。卫生专业人员应持续改善女性对产前筛查的了解,同时也要考虑女性的偏好。

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