Pusateri D W, Muder R R
Department of Medicine, Mercy Hospital of Pittsburgh.
Chest. 1990 Sep;98(3):754-6. doi: 10.1378/chest.98.3.754.
A 71-year-old man presented with herpes zoster ophthalmicus and ocular involvement. Following the institution of intravenous therapy with acyclovir, the patient developed fever, hemoptysis, and a pleural friction rub. A ventilation-perfusion lung scan showed no defects; roentgenograms showed bilateral infiltrates and a left-sided pleural effusion. The fever abated promptly following discontinuation of acyclovir, and radiographic abnormalities resolved over ten days. No other anti-infective therapy was given. To our knowledge, the syndrome of fever, pulmonary infiltrates, and pleural effusion following use of acyclovir has not been previously reported.
一名71岁男性患者出现眼带状疱疹并累及眼部。在用阿昔洛韦进行静脉治疗后，患者出现发热、咯血和胸膜摩擦音。通气-灌注肺扫描未显示异常；X线胸片显示双侧浸润及左侧胸腔积液。停用阿昔洛韦后发热迅速消退，影像学异常在十天内消失。未给予其他抗感染治疗。据我们所知，使用阿昔洛韦后出现发热、肺部浸润和胸腔积液的综合征此前尚未见报道。
