Shardakov V I, Kopaneva T G, Shuliat'eva T N, Kuznetsova N N, Nikiforova T V
Gematol Transfuziol. 1990 Jun;35(6):22-4.
The features of nonspecific defense factors were studied in 42 patients with chronic myeloid leukemia (CML) and in 18--with chronic subleukemic myelosis (CSM), in the presence of the treatment including polychemotherapy and plasmocytapheresis. Significant changes have been detected in the humoral factors of nonspecific defense (lysozyme, beta-lysins, complement components), as well as in the cellular component (phagocytic activity of the cells) in CML patients, these changes were growing with the leukemic process progressing. Plasmocytapheresis conducted produced no appreciable effect on the parameters of nonspecific resistance in the patients.
在42例慢性髓性白血病（CML）患者和18例慢性亚白血病性骨髓增生症（CSM）患者中，在包括多药化疗和血浆置换术的治疗过程中，研究了非特异性防御因子的特征。在CML患者中，已检测到非特异性防御的体液因子（溶菌酶、β-溶素、补体成分）以及细胞成分（细胞的吞噬活性）有显著变化，这些变化随着白血病进程的发展而加剧。进行的血浆置换术对患者非特异性抵抗力的参数没有明显影响。
