Critical Care and Trauma Division, The George Institute for Global Health, Sydney, NSW, Australia.
Crit Care Resusc. 2013 Sep;15(3):228-33.
To determine the frequency of pharmacological and physical cooling in non-elective general intensive care unit patients without neurological abnormalities in Australia and New Zealand, and to establish the indications for antipyretics, the prevalence of fever, and the methods of temperature measurement.
DESIGN, SETTING AND PARTICIPANTS: A point prevalence study conducted on two days in 2010, in 38 ICUs in Australia and New Zealand, examining non-elective (emergency) patients admitted with sepsis and other inflammatory abnormalities but without neurological abnormalities.
Of 506 general ICU patients surveyed on the study days, 311 had sepsis or other inflammatory abnormalities and no neurological abnormalities. These patients had a mean peak temperature of 37.3°C (SD, 0.8°C). In 100 patients (32.2%), the peak temperature was above 38°C. Paracetamol was the most common antipyretic used (152/311; 48.9%) and was administered for pain in 92/152 patients (60.5%), for pain and fever in 26/152 patients (17.1%), and for fever alone in 14/152 patients (9.2%). Patients who received paracetamol for fever had a mean peak recorded temperature of 38.3°C (SD, 0.8°C). Temperature measurements were mainly non-core (251/ 311; 81%) with axillary (116/311; 37%) and tympanic (110/ 311; 35%) measurements the most common.
Pharmacological antipyretics are used regularly for pain management rather than fever management, with paracetamol the most common antipyretic therapy. The use of NSAIDS and physical cooling is rare. Non-core temperature measurements were common.
在澳大利亚和新西兰无神经异常的非择期普通重症监护病房患者中,确定药物和物理降温的频率,并确定退热剂的适应证、发热的发生率以及体温测量方法。
设计、地点和参与者:这是一项在 2010 年两天进行的时点患病率研究,在澳大利亚和新西兰的 38 个 ICU 中,对因败血症和其他炎症异常而非神经异常而入院的非择期(急诊)患者进行了检查。
在研究日调查的 506 名普通 ICU 患者中,有 311 名患有败血症或其他炎症异常且无神经异常。这些患者的平均峰值体温为 37.3°C(标准差,0.8°C)。在 100 名患者(32.2%)中,峰值体温高于 38°C。扑热息痛是最常用的退热剂(152/311;48.9%),92/152 名患者(60.5%)因疼痛使用,26/152 名患者(17.1%)因疼痛和发热使用,14/152 名患者(9.2%)因发热单独使用。接受扑热息痛退热的患者平均记录的峰值体温为 38.3°C(标准差,0.8°C)。体温测量主要是非核心部位(251/311;81%),最常见的是腋窝(116/311;37%)和鼓膜(110/311;35%)测量。
经常使用药物退热来缓解疼痛,而非治疗发热,扑热息痛是最常用的退热疗法。非甾体抗炎药和物理降温的应用很少见。非核心部位的体温测量很常见。