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角膜前表面形态:4 种角膜地形图仪高度数据的比较。

Shape of the anterior cornea: comparison of height data from 4 corneal topographers.

机构信息

From the Department of Ophthalmology (de Jong, Koopmans, Jansonius), University Medical Center Groningen, University of Groningen, Groningen, and the Department of Physics and Medical Technology (Dubbelman), VU University Medical Center, Amsterdam, Netherlands the National University Ireland-Galway (Sheehan), Galway, Ireland.

出版信息

J Cataract Refract Surg. 2013 Oct;39(10):1570-80. doi: 10.1016/j.jcrs.2013.04.032. Epub 2013 Aug 12.

Abstract

PURPOSE

To compare the ability of clinical corneal topographers to describe the shape of the anterior cornea for optical modeling.

SETTING

University Medical Center Groningen, Groningen, Netherlands.

DESIGN

Cross-sectional study.

METHODS

The anterior corneal shape of healthy subjects was assessed with 4 topographers (Atlas Placido disk, Galilei dual Scheimpflug, Orbscan scanning slit, Pentacam single Scheimpflug). Exported height data were fit with Zernike polynomials. Mean values with the standard deviation, interdevice variability, and test-retest variability were determined for the defocus Z(2,0), astigmatism Z(2,-2) and Z(2,2), coma Z(3,-1) and Z(3,1), and spherical aberration Z(4,0) coefficients for 5.5 mm and 8.0 mm diameters.

RESULTS

At 5.5 mm, the single Scheimpflug topographer showed the smallest coefficient of repeatability; 0.31 μm for Z(2,0); 0.40 and 0.34 μm for Z(2,-2) and Z(2,2), respectively; 0.15 and 0.11 μm for Z(3,-1) and Z(3,1), respectively; and 0.08 μm for Z(4,0); the other topographers showed up to 10 times larger coefficients of repeatability. The (unsigned) mean differences between the topographers were in the range of 0.20 to 1.21 μm for Z(2,0); 0.02 to 0.31 μm and 0.06 to 0.42 μm for Z(2,-2) and Z(2,2), respectively; 0.03 to 0.18 μm and 0.03 to 0.35 μm for Z(3,-1) and Z(3,1), respectively; and 0.00 to 0.14 μm for Z(4,0). The Placido-disk topographer and single Scheimpflug topographer data corresponded best. Similar trends were found at 8.0 mm.

CONCLUSION

Test-retest variability hampered a detailed description of the anterior corneal shape at the level of individual subjects; interdevice variability compromises the exchangeability of the devices.

FINANCIAL DISCLOSURE

No author has a financial or proprietary interest in any material or method mentioned.

摘要

目的

比较临床角膜地形仪在光学建模中描述角膜前表面形态的能力。

地点

荷兰格罗宁根大学医学中心。

设计

横断面研究。

方法

使用 4 种角膜地形仪(Atlas Placido 盘、Galilei 双 Scheimpflug、Orbscan 扫描裂隙、Pentacam 单 Scheimpflug)评估健康受试者的角膜前表面形态。导出的高度数据采用 Zernike 多项式拟合。确定 5.5mm 和 8.0mm 直径的离焦 Z(2,0)、散光 Z(2,-2)和 Z(2,2)、彗差 Z(3,-1)和 Z(3,1)、球差 Z(4,0)系数的平均值及其标准差、设备间可变性和重复性。

结果

在 5.5mm 时,单 Scheimpflug 地形仪的重复性系数最小,Z(2,0)为 0.31μm;Z(2,-2)和 Z(2,2)分别为 0.40μm 和 0.34μm;Z(3,-1)和 Z(3,1)分别为 0.15μm 和 0.11μm;Z(4,0)为 0.08μm;其他地形仪的重复性系数最大可达 10 倍。各仪器间的平均差异(无符号)在 Z(2,0)为 0.20μm 到 1.21μm 之间;Z(2,-2)和 Z(2,2)分别为 0.02μm 到 0.31μm 和 0.06μm 到 0.42μm;Z(3,-1)和 Z(3,1)分别为 0.03μm 到 0.18μm 和 0.03μm 到 0.35μm;Z(4,0)为 0.00μm 到 0.14μm。Placido 盘地形仪和单 Scheimpflug 地形仪的数据最为吻合。在 8.0mm 时也出现了类似的趋势。

结论

重复性测试变异性妨碍了对个体受试者角膜前表面形态的详细描述;设备间变异性影响了设备的可交换性。

利益冲突

无作者在本文中提到的任何材料或方法上有经济或所有权利益。

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