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跛行规则:周围神经损伤后,关节补偿可保持肢体功能。

Rules to limp by: joint compensation conserves limb function after peripheral nerve injury.

机构信息

Comparative Neuromechanics Laboratory, School of Applied Physiology, Georgia Institute of Technology, GA 30332-0356, USA.

出版信息

Biol Lett. 2013 Aug 14;9(5):20130484. doi: 10.1098/rsbl.2013.0484. Print 2013 Oct 23.

DOI:10.1098/rsbl.2013.0484
PMID:23945208
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3971686/
Abstract

Locomotion persists across all manner of internal and external perturbations. The objective of this study was to identify locomotor compensation strategies in rodent models of peripheral nerve injury. We found that hip-to-toe limb length and limb angle was preferentially preserved over individual joint angles after permanent denervation of rat ankle extensor muscles. These findings promote further enquiry into the significance of limb-level function for neuromechanical control of legged locomotion.

摘要

运动在各种内部和外部干扰下持续存在。本研究旨在确定周围神经损伤啮齿动物模型中的运动补偿策略。我们发现,在大鼠踝关节伸肌永久性失神经后,髋关节到脚趾的肢体长度和肢体角度优先于各个关节角度得到保留。这些发现促进了对肢体水平功能对腿部运动神经力学控制的重要性的进一步研究。

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本文引用的文献

1
The biomechanics of locomotor compensation after peripheral nerve lesion in the rat.大鼠周围神经损伤后运动补偿的生物力学。
Behav Brain Res. 2012 Apr 15;229(2):391-400. doi: 10.1016/j.bbr.2012.01.040. Epub 2012 Jan 30.
2
Short-term effects of muscular denervation and fasciotomy on global limb variables during locomotion in the decerebrate cat.去大脑猫在运动过程中,肌肉失神经和筋膜切开术对肢体整体变量的短期影响。
Cells Tissues Organs. 2011;193(5):325-35. doi: 10.1159/000323679. Epub 2011 Mar 21.
3
Effect of slope and sciatic nerve injury on ankle muscle recruitment and hindlimb kinematics during walking in the rat.坡度和坐骨神经损伤对大鼠行走时踝关节肌肉募集和后肢运动学的影响。
J Exp Biol. 2011 Mar 15;214(Pt 6):1007-16. doi: 10.1242/jeb.051508.
4
High-speed X-ray video demonstrates significant skin movement errors with standard optical kinematics during rat locomotion.高速 X 光视频显示,在大鼠运动过程中,标准光学运动学存在明显的皮肤运动误差。
J Neurosci Methods. 2010 Jan 30;186(1):18-24. doi: 10.1016/j.jneumeth.2009.10.017. Epub 2009 Nov 10.
5
Whole limb kinematics are preferentially conserved over individual joint kinematics after peripheral nerve injury.外周神经损伤后,肢体整体运动学优先于个别关节运动学得到保留。
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6
Rate-dependent control strategies stabilize limb forces during human locomotion.速率相关控制策略稳定人体运动中的肢体力量。
J R Soc Interface. 2010 May 6;7(46):801-10. doi: 10.1098/rsif.2009.0296. Epub 2009 Oct 14.
7
Joint-level kinetic redundancy is exploited to control limb-level forces during human hopping.在人类单脚跳跃过程中,利用关节层面的动力学冗余来控制肢体层面的力。
Exp Brain Res. 2009 Jul;196(3):439-51. doi: 10.1007/s00221-009-1868-4. Epub 2009 Jun 4.
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Heterogenic feedback between hindlimb extensors in the spontaneously locomoting premammillary cat.自发运动的乳头前猫后肢伸肌之间的异质性反馈。
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Exp Brain Res. 2009 Jan;192(2):253-64. doi: 10.1007/s00221-008-1582-7. Epub 2008 Oct 7.
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Software techniques for two- and three-dimensional kinematic measurements of biological and biomimetic systems.用于生物和仿生系统二维及三维运动学测量的软件技术。
Bioinspir Biomim. 2008 Sep;3(3):034001. doi: 10.1088/1748-3182/3/3/034001. Epub 2008 Jul 1.