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跛行规则:周围神经损伤后,关节补偿可保持肢体功能。

Rules to limp by: joint compensation conserves limb function after peripheral nerve injury.

机构信息

Comparative Neuromechanics Laboratory, School of Applied Physiology, Georgia Institute of Technology, GA 30332-0356, USA.

出版信息

Biol Lett. 2013 Aug 14;9(5):20130484. doi: 10.1098/rsbl.2013.0484. Print 2013 Oct 23.

Abstract

Locomotion persists across all manner of internal and external perturbations. The objective of this study was to identify locomotor compensation strategies in rodent models of peripheral nerve injury. We found that hip-to-toe limb length and limb angle was preferentially preserved over individual joint angles after permanent denervation of rat ankle extensor muscles. These findings promote further enquiry into the significance of limb-level function for neuromechanical control of legged locomotion.

摘要

运动在各种内部和外部干扰下持续存在。本研究旨在确定周围神经损伤啮齿动物模型中的运动补偿策略。我们发现,在大鼠踝关节伸肌永久性失神经后,髋关节到脚趾的肢体长度和肢体角度优先于各个关节角度得到保留。这些发现促进了对肢体水平功能对腿部运动神经力学控制的重要性的进一步研究。

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1
The biomechanics of locomotor compensation after peripheral nerve lesion in the rat.大鼠周围神经损伤后运动补偿的生物力学。
Behav Brain Res. 2012 Apr 15;229(2):391-400. doi: 10.1016/j.bbr.2012.01.040. Epub 2012 Jan 30.

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