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原发性胃癌手术切除10年后发生膀胱转移:1例病例报告并文献复习

Occurrence of bladder metastasis 10 years after surgical removal of a primary gastric cancer: a case report and review of the literature.

作者信息

András Csilla, Tóth László, Pósán János, Csiki Emese, Tanyi Miklós, Csiki Zoltán, Garami Zoltán, Enyedi Attila, Flaskó Tibor, Horváth Zsolt

机构信息

Institute of Oncology, Medical and Health Science Center, University of Debrecen, Nagyerdei krt, 98, 4032 Debrecen, Hungary.

出版信息

J Med Case Rep. 2013 Aug 14;7:204. doi: 10.1186/1752-1947-7-204.

Abstract

INTRODUCTION

Secondary bladder neoplasms are uncommon and they represent only 2% of all malignant bladder tumors.

CASE PRESENTATION

The authors present a case of a 59-year-old Caucasian man with a primary gastric adenocarcinoma that had been surgically removed 10 years before he developed bladder metastasis. He presented with low abdominal pain after 10 years without any symptoms. Cystoscopy and an abdominal computed tomography scan showed a bladder tumor. A transurethral resection of the bladder tumor was performed. A histological examination revealed an adenocarcinoma, which turned out to be a metastasis of the primary gastric tumor. One year later, abdominal surgery revealed peritoneal metastases.

CONCLUSION

This is the first known case in Europe where bladder metastasis occurred 10 years after surgical removal of a primary gastric neoplasm. There are only four cases in the literature where metastases of the peritoneum developed 11 years after surgical removal of a primary gastric tumor.

摘要

引言

继发性膀胱肿瘤并不常见,仅占所有恶性膀胱肿瘤的2%。

病例报告

作者报告了一例59岁的白种男性病例,其原发性胃腺癌在发生膀胱转移前10年已接受手术切除。10年来他一直无症状,之后出现下腹部疼痛。膀胱镜检查和腹部计算机断层扫描显示有膀胱肿瘤。对膀胱肿瘤进行了经尿道切除术。组织学检查显示为腺癌,结果是原发性胃肿瘤的转移。一年后,腹部手术发现有腹膜转移。

结论

这是欧洲首例已知的在原发性胃肿瘤手术切除10年后发生膀胱转移的病例。文献中仅有4例在原发性胃肿瘤手术切除11年后发生腹膜转移的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7421/3766071/1619ae9d9611/1752-1947-7-204-1.jpg

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