Christensen Brian, Han Michael, Dillon Jasjit K
Former Dental Student, School of Dentistry, University of Washington, Seattle, WA; Current Resident, Department of Oral and Maxillofacial Surgery, Louisiana State University Health Science Center, New Orleans, LA.
J Oral Maxillofac Surg. 2013 Dec;71(12):2068-76. doi: 10.1016/j.joms.2013.05.027. Epub 2013 Aug 12.
The purpose of this retrospective cohort study was to evaluate the demographic, social, treatment, and hospital course variables associated with length of stay (LOS), intensive care unit (ICU) use, and additional operating room (OR) use in patients admitted for odontogenic infections.
A retrospective chart review was conducted in patients admitted for odontogenic infections at Harborview Medical Center from July 1, 2001 through June 30, 2011.
In total, 318 patient charts were reviewed and included. In the multivariate linear regression analysis on LOS, the variables drug abuse, location of treatment, number of spaces involved, side or location of infection, ICU use, length of ICU stay, additional OR use, peak temperature, admission white blood cell count, peak white blood cell count, and peak blood sugar accounted for 68.2% of the variation. In the multivariate logistic regression analysis on ICU use, the variables OR time, number of spaces involved, and peak blood sugar accounted for 32.5% of the variation. LOS was the only variable significantly associated with additional OR use in the multivariate analysis.
An understanding of the key variables involved in LOS in patients with odontogenic infections has been greatly improved by recent studies and reinforced by the present study. The authors present a starting point for a greater understanding of the variables involved in ICU use, but much more work is needed to address variables identifying patients requiring reoperation. Future studies should aim to create multivariate models explaining all variations in these outcome variables.
本回顾性队列研究旨在评估与牙源性感染入院患者的住院时间(LOS)、重症监护病房(ICU)使用情况及额外手术室(OR)使用情况相关的人口统计学、社会、治疗及住院过程变量。
对2001年7月1日至2011年6月30日在哈博维尤医疗中心因牙源性感染入院的患者进行回顾性病历审查。
共审查并纳入318份患者病历。在关于住院时间的多变量线性回归分析中,药物滥用、治疗地点、受累间隙数量、感染部位或位置、ICU使用情况、ICU住院时间、额外手术室使用情况、最高体温、入院白细胞计数、最高白细胞计数及最高血糖等变量解释了68.2%的变异。在关于ICU使用情况的多变量逻辑回归分析中,手术室时间、受累间隙数量及最高血糖等变量解释了32.5%的变异。在多变量分析中,住院时间是与额外手术室使用情况显著相关的唯一变量。
近期研究极大地增进了对牙源性感染患者住院时间相关关键变量的理解,本研究进一步强化了这一点。作者提供了一个更好理解ICU使用相关变量的起点,但仍需开展更多工作以确定需要再次手术的患者相关变量。未来研究应致力于建立多变量模型来解释这些结局变量的所有变异。