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针刺引产

Acupuncture for induction of labour.

作者信息

Smith Caroline A, Crowther Caroline A, Grant Suzanne J

机构信息

Center for Complementary Medicine Research, University of Western Sydney, Locked Bag 1797, Sydney, New South Wales, Australia, 2751.

出版信息

Cochrane Database Syst Rev. 2013 Aug 15(8):CD002962. doi: 10.1002/14651858.CD002962.pub3.

Abstract

BACKGROUND

This is one of a series of reviews of methods of cervical ripening and labour induction using standardised methodology. The use of complementary therapies is increasing and some women look to complementary therapies during pregnancy and childbirth to be used alongside conventional medical practice. Acupuncture involves the insertion of very fine needles into specific points of the body. The limited observational studies to date suggest acupuncture for induction of labour appears safe, has no known adverse effects to the fetus, and may be effective. However, the evidence regarding the clinical effectiveness of this technique is limited.

OBJECTIVES

To determine the effectiveness and safety of acupuncture for third trimester cervical ripening or induction of labour.

SEARCH METHODS

We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (23 November 2012), PubMed (1966 to 23 November 2012), Embase (1980 to 23 November 2012), Dissertation Abstracts (1861 to 23 November 2012), CINAHL (1982 to 23 November 2012), the WHO International Clinical Trials Registry Portal (ICTRP) (23 November 2012) and bibliographies of relevant papers.

SELECTION CRITERIA

Clinical trials comparing acupuncture used for third trimester cervical ripening or labour induction with placebo/no treatment or other methods listed above it on a predefined list of labour induction methods.

DATA COLLECTION AND ANALYSIS

Two review authors independently assessed trials for inclusion, evaluated methodological quality and extracted data.

MAIN RESULTS

The original review included three trials and seven trials were excluded. This updated review includes 14 trials, and excludes eight trials. Three trials previously excluded due to no clinically relevant outcomes are now included. Eight new trials were included, and four new trials were excluded. We included 14 trials with data reporting on 2220 women.Trials reported on three primary outcomes only caesarean section, serious neonatal morbidity and maternal mortality. No trial reported on vaginal delivery not achieved within 24 hours; and uterine hyperstimulation with fetal heart rate (FHR) changes. There was no difference in caesarean deliveries between acupuncture and the sham control (average risk ratio (RR) 0.95, 95% confidence interval (CI) 0.69 to 1.30, six trials, 654 women), and acupuncture versus usual care (average RR 0.69, 95% CI 0.40, 1.20, six trials, 361 women). There was no difference in neonatal seizures between acupuncture and the sham group (RR 1.01, 95% CI 0.06 to 16.04, one trial, 364 women).There was some evidence of a change in cervical maturation for women receiving acupuncture compared with the sham control, (mean difference (MD) 0.40. 95%CI 0.11 to 0.69, one trial, 125 women), and when compared with usual care (MD 1.30, 95% CI 0.11 to 2.49, one trial, 67 women). The length of labour was shorter in the usual care group compared with acupuncture (average standardised mean difference (SMD) 0.67, 95% CI 0.18 to 1.17, one trial 68 women). There were no other statistically significant differences between groups. Few studies reported on many clinically relevant outcomes. One trial was at a low risk of bias on all domains.

AUTHORS' CONCLUSIONS: Overall, there have been few studies assessing the role of acupuncture for induction of labour. Before implications for clinical practice can be made there is a need for well-designed randomised controlled trials to evaluate the role of acupuncture to induce labour and for trials to assess clinically meaningful outcomes.

摘要

背景

这是一系列使用标准化方法对宫颈成熟和引产方法进行综述的文章之一。辅助疗法的使用正在增加,一些女性在怀孕和分娩期间希望将辅助疗法与传统医疗方法一起使用。针灸是将非常细的针插入身体的特定穴位。迄今为止有限的观察性研究表明,针灸引产似乎是安全的,对胎儿没有已知的不良影响,并且可能有效。然而,关于该技术临床有效性的证据有限。

目的

确定针灸用于孕晚期宫颈成熟或引产的有效性和安全性。

检索方法

我们检索了Cochrane妊娠与分娩组试验注册库(2012年11月23日)、PubMed(1966年至2012年11月23日)、Embase(1980年至2012年11月23日)、学位论文摘要(1861年至2012年11月23日)、CINAHL(1982年至2012年11月23日)、世界卫生组织国际临床试验注册平台(ICTRP)(2012年11月23日)以及相关论文的参考文献。

选择标准

将用于孕晚期宫颈成熟或引产的针灸与安慰剂/不治疗或在预定义引产方法列表中排在其上方的其他方法进行比较的临床试验。

数据收集与分析

两位综述作者独立评估试验是否纳入,评估方法学质量并提取数据。

主要结果

原综述纳入了3项试验,排除了7项试验。本次更新后的综述纳入了14项试验,排除了8项试验。之前因无临床相关结局而排除的3项试验现在纳入了。纳入了8项新试验,排除了4项新试验。我们纳入了14项试验,这些试验报告了2220名女性的数据。试验仅报告了三项主要结局:剖宫产、严重新生儿发病率和孕产妇死亡率。没有试验报告24小时内未实现阴道分娩;以及伴有胎儿心率(FHR)变化的子宫过度刺激。针灸组与假手术对照组之间的剖宫产率无差异(平均风险比(RR)0.95,95%置信区间(CI)0.69至1.30,6项试验,654名女性),针灸组与常规护理组之间也无差异(平均RR 0.69,95%CI 0.40至1.20,6项试验,361名女性)。针灸组与假手术组之间的新生儿惊厥发生率无差异(RR 1.01,95%CI 0.06至16.04,1项试验,364名女性)。有一些证据表明,与假手术对照组相比,接受针灸治疗的女性宫颈成熟度有变化(平均差(MD)0.40,95%CI 0.11至0.69,1项试验,125名女性),与常规护理组相比也有变化(MD 1.30,95%CI 0.11至2.49,1项试验,67名女性)。常规护理组的产程比针灸组短(平均标准化均数差(SMD)0.67,95%CI 0.18至1.17,1项试验,68名女性)。两组之间没有其他具有统计学意义的差异。很少有研究报告许多临床相关结局。1项试验在所有领域的偏倚风险较低。

作者结论

总体而言,评估针灸引产作用的研究很少。在得出对临床实践的影响之前,需要进行精心设计的随机对照试验来评估针灸引产的作用,并进行试验以评估具有临床意义的结局。

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