Li Xing-Bo, Qi Yao-Dong, Liu Hai-Tao, Zhang Jin, Zhang Zhao, Zhang Ben-Gang
Key Laboratory of Bioactive Substance and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China.
Zhongguo Zhong Yao Za Zhi. 2013 May;38(10):1543-7.
Sixteen compounds were isolated from Conioselinum vaginatum by silica column chromatography over silica gel and Sephadex LH-20, as well as recrystallization. On the basis of their physical and chemical properties and spectral data, their structures were identified as ligustilide (1), 1,3-dilinolein (2), coniferaldehyde (3), myristicin (4), stigmasterol (5), beta-sitosterol (6), vanillin (7), pregnenolone (8), bergapten (9), xanthotoxin (10), methyl indole-3-carboxylate (11), ferulic acid (12), (E)-3-methoxy-4,5-methylenedioxy-cinnamic alcohol (13), p-hydroxybenzaldehyde (14), 3-methoxy-4,5-methylenedioxy-acetophenone (15), and alpha-(ethoxymethyl)-4-hydroxy- benzenemethanol (16). Among them, compound 15 was a new natural product, and compounds 2, 3, 10, 11, 14, and 16 were obtained from this genus for the first time.
通过硅胶柱色谱、Sephadex LH - 20柱色谱以及重结晶从鞘山芹中分离得到了16种化合物。根据它们的理化性质和光谱数据，其结构被鉴定为藁本内酯(1)、1,3 - 二亚油酸甘油酯(2)、松柏醛(3)、肉豆蔻醚(4)、豆甾醇(5)、β - 谷甾醇(6)、香草醛(7)、孕烯醇酮(8)、补骨脂素(9)、花椒毒素(10)、吲哚 - 3 - 甲酸甲酯(11)、阿魏酸(12)、(E)-3 - 甲氧基 - 4,5 - 亚甲二氧基肉桂醇(13)、对羟基苯甲醛(14)、3 - 甲氧基 - 4,5 - 亚甲二氧基苯乙酮(15)和α-(乙氧基甲基)-4 - 羟基苯甲醇(16)。其中，化合物15是一种新的天然产物，化合物2、3、10、11、14和16首次从该属植物中获得。
