Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta, T2N 4Z6, Canada.
Trends Parasitol. 2013 Sep;29(9):438-48. doi: 10.1016/j.pt.2013.07.006. Epub 2013 Aug 12.
The health and economic importance of parasitic nematodes cannot be overstated. Moreover, they offer a complex and diverse array of life strategies, raising a multitude of evolutionary questions. Researchers are applying population genetics to parasitic nematodes in order to disentangle some aspects of their life strategies, improve our knowledge about disease epidemiology, and design control strategies. However, population genetics studies of nematodes have been constrained due to the difficulty in sampling nematodes and developing molecular markers. In this context, new computational and sequencing technologies represent promising tools to investigate population genomics of parasitic, non-model, nematode species in an epidemiological context.
寄生虫线虫的健康和经济重要性怎么强调都不为过。此外，它们提供了一系列复杂多样的生存策略，提出了许多进化问题。研究人员正在将群体遗传学应用于寄生线虫，以厘清其生存策略的某些方面，增进我们对疾病流行病学的认识，并设计控制策略。然而，由于线虫采样和分子标记开发的困难，线虫的群体遗传学研究受到了限制。在这种情况下，新的计算和测序技术为在流行病学背景下研究寄生、非模式线虫物种的群体基因组学提供了有希望的工具。
