Department of Chemistry, Inha University, 100 Inharo, Namku, Incheon 402-751, South Korea.
J Chromatogr A. 2013 Sep 20;1308:1-24. doi: 10.1016/j.chroma.2013.07.107. Epub 2013 Aug 5.
Open tubular (OT) capillary columns have been increasingly used in a variety of fields of separation science such as CEC, LC, and SPE. Especially their application in CEC has attracted a lot of attention for their outstanding separation performance. Various forms of OT stationary phase materials have been employed such as in-situ prepared polymers, molecular imprinted polymers (MIPs), brush ligands, host ligands, block copolymers, aptamers, carbon nanotubes, polysaccharides, proteins, tentacles, nanoparticles, monoliths, and polyelectrolyte multi-layers. They have been prepared either in the chemically bound format or physically adsorbed format. Sol-gel technologies and nanoparticles have been sometimes involved in their preparation. There have been also some unique miscellaneous studies, for example, adopting preferentially adsorbed mobile phase components as stationary phases. In this review, recent progresses since mostly 2007 will be critically discussed in detail with some summarized descriptions for the work before the date.
开管（OT）毛细管柱已在诸如 CEC、LC 和 SPE 等分离科学的多个领域中得到越来越多的应用。特别是它们在 CEC 中的应用因其出色的分离性能而引起了广泛关注。已经采用了各种形式的 OT 固定相材料，例如原位制备的聚合物、分子印迹聚合物（MIPs）、刷配体、主体配体、嵌段共聚物、适体、碳纳米管、多糖、蛋白质、触手、纳米颗粒、整体柱和聚电解质多层膜。它们以化学键合形式或物理吸附形式制备。溶胶-凝胶技术和纳米颗粒有时也用于它们的制备。也有一些独特的杂项研究，例如，采用优先吸附的流动相组分作为固定相。在这篇综述中，我们将主要讨论自 2007 年以来的最新进展，并对该日期之前的工作进行一些总结描述。
