Bartel P, Göcking K, Janzen J, Pannek J
Neuro-Urologie, Schweizer Paraplegiker-Zentrum, Guido A. Zäch Straße 1, CH-6207, Nottwil, Schweiz.
Urologe A. 2013 Sep;52(9):1248-50. doi: 10.1007/s00120-013-3300-8.
In patients with spinal cord injury (SCI) the rate of squamous cell carcinomas (SCC) among bladder tumors is increased compared to the general population. An increased life expectancy is achieved by modern HIV treatment so that more AIDS-unrelated malignomas, e.g. bladder tumors, occur in these patients. Therefore, the risk for SCC in this group of patients is increased in patients with SCI and HIV but the combination of these two diseases is rare. We report the first case of SCC in a patient with SCI and HIV. Initial symptoms of bladder tumors in patients with SCI are often unspecific; therefore, in cases with new onset hematuria, recurrent urinary tract infections and changes in bladder function, cystoscopy and computed tomography (CT) scanning should be considered.
与普通人群相比，脊髓损伤（SCI）患者膀胱肿瘤中鳞状细胞癌（SCC）的发生率有所增加。现代抗逆转录病毒治疗使艾滋病患者的预期寿命延长，从而使这些患者出现更多与艾滋病无关的恶性肿瘤，如膀胱肿瘤。因此，SCI和HIV患者发生SCC的风险增加，但这两种疾病同时存在的情况较为罕见。我们报告了首例SCI合并HIV患者发生SCC的病例。SCI患者膀胱肿瘤的初始症状往往不具特异性；因此，对于出现新发血尿、复发性尿路感染和膀胱功能改变的病例，应考虑进行膀胱镜检查和计算机断层扫描（CT）。
