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皮质脊髓束的扩散张量纤维束成像能否正确反映运动功能?

Does diffusion tensor tractography of the corticospinal tract correctly reflect motor function?

作者信息

Min Zhi-gang, Rana Netra, Niu Chen, Ji Huan-mei, Zhang Ming

机构信息

Department of Radiology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, PR China.

出版信息

Med Princ Pract. 2014;23(2):174-6. doi: 10.1159/000353463. Epub 2013 Aug 13.

DOI:10.1159/000353463
PMID:23949557
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5586848/
Abstract

OBJECTIVE

To investigate the consistency of diffusion tensor tractography of the corticospinal tract on motor function. CLINICAL PRESENTATIONS AND INTERVENTION: Three patients with brain tumor were admitted to our hospital with impaired motor function. Diffusion tensor imaging (DTI) and tractography were performed in these patients to assess their affected corticospinal tract. The corticospinal tract showed interruption with moderately impaired motor function in 2 patients. The third case had significantly weakened muscle strength on the left upper limb but an intact right corticospinal tract.

CONCLUSION

These cases showed that the corticospinal tracts obtained by DTI with tractography were inconsistent with motor function. Hence, DTI should be interpreted with caution.

摘要

目的

研究皮质脊髓束的扩散张量纤维束成像与运动功能的一致性。临床表现及干预措施:三名脑肿瘤患者因运动功能受损入住我院。对这些患者进行了扩散张量成像(DTI)和纤维束成像,以评估其受影响的皮质脊髓束。两名患者的皮质脊髓束显示中断,运动功能中度受损。第三例患者左上肢肌力明显减弱,但右侧皮质脊髓束完整。

结论

这些病例表明,通过DTI纤维束成像获得的皮质脊髓束与运动功能不一致。因此,对DTI的解读应谨慎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f01/5586848/1a745cb38089/mpp-0023-0174-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f01/5586848/98150f860228/mpp-0023-0174-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f01/5586848/1530a33e55bf/mpp-0023-0174-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f01/5586848/1a745cb38089/mpp-0023-0174-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f01/5586848/98150f860228/mpp-0023-0174-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f01/5586848/1530a33e55bf/mpp-0023-0174-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f01/5586848/1a745cb38089/mpp-0023-0174-g03.jpg

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