Shilo S, Hirsch H J
Endocrine Clinic, Shaare Zedek Medical Center, Jerusalem, Israel.
J Intern Med. 1990 Aug;228(2):197-8. doi: 10.1111/j.1365-2796.1990.tb00216.x.
Compensated hypothyroidism was diagnosed in a 36-year-old female who presented with breast tenderness and mild galactorrhoea. T4 was 5.8 mcg dl-1 and T3RU was 22.5%, while TSH and prolactin were very mildly elevated (6.5 mU ml-1 and 26.1 ng ml-1, respectively). The TRH test showed an exaggerated response. TSH increased to 43 mU ml-1, and prolactin levels reached 161 ng ml-1. Treatment with T4 decreased the TSH and prolactin levels to within the normal range, and prevented the galactorrhoea. The case presented here demonstrates that galactorrhoea can be present even with mild hypothyroidism.
一名36岁女性被诊断为代偿性甲状腺功能减退，她表现为乳房压痛和轻度溢乳。甲状腺素（T4）为5.8微克/分升，甲状腺素摄取率（T3RU）为22.5%，而促甲状腺激素（TSH）和催乳素仅轻度升高（分别为6.5毫单位/毫升和26.1纳克/毫升）。促甲状腺激素释放激素（TRH）试验显示反应过度。TSH升至43毫单位/毫升，催乳素水平达到161纳克/毫升。用T4治疗使TSH和催乳素水平降至正常范围，并防止了溢乳。此处报告的病例表明，即使是轻度甲状腺功能减退也可能出现溢乳。
