Faculty of Medicine, Department of Psychiatry, Padjadjaran University/Hasan Sadikin Hospital, Bandung, Indonesia.
Am J Addict. 2013 Sep-Oct;22(5):425-31. doi: 10.1111/j.1521-0391.2013.00334.x. Epub 2013 May 17.
The goal of methadone maintenance treatment (MMT) is to reduce the harm and to improve patients' quality of life (Qol). However, the Qol is also influenced by other co-occurring disorders. Data regarding the Qol and the co-occurrence of these disorders is lacking in low-middle income countries. We therefore describe the prevalence of physical, psychiatric, and drug abuse co-occurring disorders among MMT patients in Indonesia and determine the association between the severity of the co-occurring disorders and the Qol.
Data were collected in 112 injection drug abusers (IDUs) attending a MMT program in West Java, Indonesia, using validated questionnaires, medical records and laboratory testing. For comparison, 154 IDUs not enrolled in MMT were recruited by respondent driven sampling.
The most frequent co-occurring disorders were hepatitis C (92%), HIV (77%), benzodiazepine abuse (56%), and anxiety disorders (32%). IDUs in MMT had one (26%), two (47%), or three (27%) co-occurring disorders. Higher severity in psychiatric and physical problems was associated with poorer Qol. IDUs not enrolled in MMT had similar co-occurring problems.
The prevalence of co-occurring disorders in IDUs in Indonesia is high and they influence their Qol.
Therefore, comprehensive treatment, especially focusing on the common co-occurring disorders should be provided in MMT to improve the Qol.
美沙酮维持治疗(MMT)的目标是减少危害,提高患者的生活质量(Qol)。然而,Qol 也受到其他共病的影响。关于这些共病的 Qol 数据在中低收入国家中缺乏。因此,我们描述了印度尼西亚 MMT 患者中身体、精神和药物滥用共病的发生率,并确定了共病严重程度与 Qol 之间的关联。
在印度尼西亚西爪哇的一项 MMT 计划中,使用经过验证的问卷、医疗记录和实验室检测,收集了 112 名注射吸毒者(IDU)的数据。为了比较,通过应答者驱动抽样招募了 154 名未参加 MMT 的 IDU。
最常见的共病是丙型肝炎(92%)、艾滋病毒(77%)、苯二氮䓬类药物滥用(56%)和焦虑障碍(32%)。MMT 中的 IDU 有一个(26%)、两个(47%)或三个(27%)共病。精神和身体问题的严重程度越高,Qol 越差。未参加 MMT 的 IDU 有类似的共病问题。
印度尼西亚 IDU 中并存障碍的患病率很高,会影响他们的 Qol。
因此,在 MMT 中应提供综合治疗,特别是针对常见的共病,以提高 Qol。