The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), 36 Mingxin Road, Liwan District, Guangzhou, 510370, Guangdong Province, China.
Subst Abuse Treat Prev Policy. 2021 Jan 13;16(1):9. doi: 10.1186/s13011-021-00343-4.
Anxiety, an important factor that affects the therapeutic effect and preservation rate of methadone maintenance treatment, has a high prevalence among MMT patients. This study aims to investigate the effects of treatment status and life quality on anxiety in MMT patients.
One hundred and Seventy-seven methadone maintenance treatment users in Guangzhou, China were evaluated. The socio-demographic, duration and MMT-related characteristics were documented. Anxiety level and quality of life were evaluated by Beck Anxiety inventory (BAI) and the Quality of Life-Drug Addiction (QOL-DA) respectively. The correlation between different factors and BAI score was also analyzed.
The BAI total score and the QOL-DA score were 7.1±8.2, 163.5±21.4 respectively. 30.5% of the subjects showed mild to severe anxiety. Treatment interruption and QOL-DA score had strong correlations with the score of BAI, with correlation coefficients of 0.17 and - 0.08 respectively.
Anxiety symptoms were commonly presented in MMT patients. Treatment interruption and quality of life are two major factors affecting anxiety of MMT patients.
焦虑是影响美沙酮维持治疗疗效和保持率的重要因素，在美沙酮维持治疗患者中普遍存在。本研究旨在探讨治疗状况和生活质量对美沙酮维持治疗患者焦虑的影响。
对中国广州的 177 名美沙酮维持治疗使用者进行评估。记录社会人口学、治疗持续时间和与美沙酮维持治疗相关的特征。使用贝克焦虑量表（BAI）和生活质量-药物成瘾量表（QOL-DA）评估焦虑水平和生活质量。还分析了不同因素与 BAI 评分之间的相关性。
BAI 总分和 QOL-DA 评分分别为 7.1±8.2、163.5±21.4。30.5%的受试者表现出轻度至重度焦虑。治疗中断和 QOL-DA 评分与 BAI 评分具有很强的相关性，相关系数分别为 0.17 和-0.08。
焦虑症状在美沙酮维持治疗患者中较为常见。治疗中断和生活质量是影响美沙酮维持治疗患者焦虑的两个主要因素。
