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接受卵母细胞冷冻保存以保留生育能力的育龄妇女如何看待这一过程?

What do reproductive-age women who undergo oocyte cryopreservation think about the process as a means to preserve fertility?

机构信息

New York University, Fertility Center at New York University Langone Medical Center, New York University School of Medicine, New York, New York.

出版信息

Fertil Steril. 2013 Nov;100(5):1343-9. doi: 10.1016/j.fertnstert.2013.07.201. Epub 2013 Aug 13.

Abstract

OBJECTIVE

To better understand women's beliefs, priorities, and attitudes toward oocyte cryopreservation, to appreciate the extent of their reproductive education, and to track the reproductive paths of women who chose to undergo oocyte cryopreservation treatment.

DESIGN

An anonymous 30-question survey.

SETTING

Not applicable.

PATIENT(S): From 2005-2011, 478 women completed ≥1 oocyte cryopreservation treatment cycle at our center to defer reproduction.

INTERVENTION(S): None.

MAIN OUTCOME MEASURE(S): Demographics, motivations, desires, fertility knowledge, and outcomes related to oocyte cryopreservation.

RESULT(S): A total of 183 patients (38%) completed the survey with >80% being aged ≥35 years; white; having no partner at time of oocyte cryopreservation; undergoing oocyte cryopreservation after an optimal reproductive age; feeling they had improved their reproductive future after oocyte cryopreservation and being empowered by the process; aware of age-related infertility; sensing popular media falsely portrayed the upper age limit for natural conception; and recorded lack of partner as the primary rationale for not yet starting a family. Nineteen percent of respondents added that workplace inflexibility contributed to their reproductive dilemma. Half stated they learned about oocyte cryopreservation from a friend; others became aware through a medical provider, the media, and the internet. Most patients (93%) have not yet returned to use their frozen oocytes; 11 stated they had. Overall, 20% reported a successful conception after oocyte cryopreservation.

CONCLUSION(S): Surveying oocyte cryopreservation patients provides a glimpse into the knowledge base and motivations surrounding current female reproductive practices. Oocyte cryopreservation technology may prove to bridge the gap between reproductive prime and when a woman is realistically "ready" to have children.

摘要

目的

更好地了解女性对卵母细胞冷冻保存的信念、优先事项和态度,了解她们的生殖教育程度,并追踪选择进行卵母细胞冷冻保存治疗的女性的生殖路径。

设计

匿名的 30 个问题调查。

地点

不适用。

患者

2005 年至 2011 年,我们中心有 478 名女性完成了≥1 个卵母细胞冷冻保存周期以推迟生育。

干预措施

无。

主要观察指标

与卵母细胞冷冻保存相关的人口统计学、动机、愿望、生育知识和结局。

结果

共有 183 名患者(38%)完成了调查,其中 80%以上的患者年龄≥35 岁;白人;在进行卵母细胞冷冻保存时没有伴侣;在最佳生育年龄后进行卵母细胞冷冻保存;感觉卵母细胞冷冻保存改善了她们的生殖前景,并对这一过程充满信心;意识到与年龄相关的不孕;感觉到大众媒体错误地描绘了自然受孕的最高年龄限制;并记录了没有伴侣是尚未组建家庭的主要原因。19%的受访者补充说,工作场所缺乏灵活性是导致她们生殖困境的原因之一。一半的受访者表示,她们从朋友那里了解到卵母细胞冷冻保存;其他人则通过医疗服务提供者、媒体和互联网了解到这一信息。大多数患者(93%)尚未返回使用她们冷冻的卵母细胞;11 人表示已经使用。总体而言,20%的患者报告在卵母细胞冷冻保存后成功受孕。

结论

对卵母细胞冷冻保存患者进行调查,可以了解当前女性生殖实践的知识基础和动机。卵母细胞冷冻保存技术可能有助于弥合生殖高峰期和女性真正“准备”要孩子之间的差距。

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