Tandoğan Özden, Küğcümen Gözde, Satılmış İlkay Güngör
Department of Nursing, İstanbul Arel University, Cevizlibağ, Istanbul, Turkey, 34020.
Department of Midwifery, School of Health Science, Istanbul Medipol University, Kavacık, Istanbul, Turkey, 34810.
J Assist Reprod Genet. 2025 Mar 1. doi: 10.1007/s10815-025-03425-5.
The aim of this systematic review and meta-analysis was to determine the acceptance rates and reasons for social oocyte cryopreservation (SOC) in the general population (subgroup 1) and healthcare professionals/students (subgroup 2) according to the current literature. Relevant studies published between 2007 and Sept 2023 were identified from electronic databases, including PubMed, EBSCO MEDLINE Complete, Web of Science, Science Direct, Scopus, and CINAHL. Quantitative studies reporting women's acceptance rates and reasons for social oocyte cryopreservation were eligible. A total of 20 quantitative studies were included in this process. Meta-analyses were conducted using random-effects models to evaluate study effect sizes. A total of 20 articles were analyzed. While the acceptance rate of SOC women in the general population was 56.5% (95% CI = 47.8-64.9%; τ = 0.98, df = 20; p < 0.001), this rate was between 42 and 66% in female healthcare professionals/students (p > 0.05; I = 98.46%; df = 20; p < 0.001). Among the acceptable reasons for SOC, cost-recovery (67.9%, 95% CI = 58-76%, I = 97.88%, τ = 0.95, df = 6; p < 0.001) and inability to find a suitable partner (45.7%, 95% CI = 32.6-59.5%; I = 97.96%, df = 10; p < 0.001) stand out. Acceptance rates did not differ significantly between the general population and healthcare professionals/students' inability to find a suitable partner (p > 0.05). The meta-analysis shows that more than half of women accept SOC, with the acceptance rate increasing in the absence of a partner and if the cost is affordable.Trial registration CRD42023455656.
本系统评价和荟萃分析的目的是根据现有文献确定普通人群（亚组1）和医疗保健专业人员/学生（亚组2）对社会卵子冷冻（SOC）的接受率及原因。通过电子数据库检索2007年至2023年9月发表的相关研究，包括PubMed、EBSCO MEDLINE Complete、Web of Science、ScienceDirect、Scopus和CINAHL。纳入报告女性社会卵子冷冻接受率及原因的定量研究。本过程共纳入20项定量研究。采用随机效应模型进行荟萃分析以评估研究效应大小。共分析20篇文章。普通人群中社会卵子冷冻女性的接受率为56.5%（95%CI = 47.8 - 64.9%；τ = 0.98，自由度 = 20；p < 0.001），而女性医疗保健专业人员/学生的这一接受率在42%至66%之间（p > 0.05；I² = 98.46%；自由度 = 20；p < 0.001）。在社会卵子冷冻可接受的原因中，成本回收（67.9%，95%CI = 58 - 76%，I² = 97.88%，τ = 0.95，自由度 = 6；p < 0.001）和找不到合适伴侣（45.7%，95%CI = 32.6 - 59.5%；I² = 97.96%，自由度 = 10；p < 0.001）最为突出。普通人群和医疗保健专业人员/学生因找不到合适伴侣导致的接受率无显著差异（p > 0.05）。荟萃分析表明，超过一半的女性接受社会卵子冷冻，在没有伴侣且成本可承受的情况下接受率会增加。试验注册号CRD42023455656。
