高效的无金属合成各种吡啶并[2',1':2,3]咪唑并[4,5-b]喹啉。
Efficient metal-free synthesis of various pyrido[2',1':2,3]imidazo- [4,5-b]quinolines.
机构信息
Institut de Chimie Organique et Analytique (ICOA), Université d'Orléans, UMR-CNRS 7311, BP 6759, rue de Chartres, 45067 Orléans cedex 2 (France), Fax: (+33) 2-38-41-72-81.
出版信息
Chemistry. 2013 Sep 9;19(37):12249-53. doi: 10.1002/chem.201300961. Epub 2013 Aug 16.
PMID:23955568
Abstract
Dancing with diversity: The synthesis of diverse pyrido[2',1':2,3]imidazo[4,5-b]quinolines bearing several substitution patterns was developed based on combining a multicomponent reaction (Groebke-Blackburn-Bienaymé reaction) with an original cyclization as a secondary transformation (see scheme; DBU = 1,8-diazabicyclo[5.4.0]undec-7-ene).
摘要
舞动多样性
基于多组分反应（Groebke-Blackburn-Bienaymé 反应）与原始环化作为二次转化的结合（见方案；DBU = 1,8-二氮杂二环[5.4.0]十一-7-烯），开发了多种取代模式的吡啶并[2',1':2,3]咪唑并[4,5-b]喹啉的综合方法。
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