Kumar Senthil, Mahabob Nazargi
Department of Oral Medicine and Radiology, K.S.R. Institute of Dental Science and Research, Thokkavadi, Thiruchengode, Namakkal, Tamil Nadu, India.
J Pharm Bioallied Sci. 2013 Jul;5(Suppl 2):S182-4. doi: 10.4103/0975-7406.114326.
Hypodontia is defined as the developmental absence of one or more tooth and it can present in varying degrees of severity and severe hypodontia has been defined as the absence of six teeth, excluding third molars. Radiation plays an important role in the treatment of head and neck cancer, in spite of its benefits, radiation has several side-effects in the head and neck region. This article highlights a case report, where hypodontia, hypoplasia of mandible, stunded permanent teeth roots, microdontia, inversion of tooth bud were observed in 19 years old patient who was diagnosed with Langerhans cell histiocytosis at her age of 3 years she had received a combination of radiotherapy and chemotherapy for a period of 1 year and radiation of 50 Gy was used in the head and neck region. Radiographs were taken and it revealed abnormal changes in growth and development of bone and teeth.
牙缺失被定义为一颗或多颗牙齿的发育性缺失，其严重程度各不相同，严重牙缺失被定义为除第三磨牙外缺失六颗牙齿。放射治疗在头颈部癌症的治疗中起着重要作用，尽管有诸多益处，但放射治疗在头颈部区域会产生一些副作用。本文重点介绍了一例病例报告，在一名19岁患者中观察到牙缺失、下颌骨发育不全、恒牙牙根发育停滞、小牙症、牙胚倒置，该患者在3岁时被诊断为朗格汉斯细胞组织细胞增多症，曾接受了为期1年的放疗和化疗联合治疗，头颈部区域使用了50戈瑞的辐射剂量。拍摄了X光片，结果显示骨骼和牙齿的生长发育出现异常变化。
