Skinner H B
Department of Orthopaedic Surgery, School of Medicine, University of California, San Francisco 94143.
Orthopedics. 1990 Aug;13(8):843-6. doi: 10.3928/0147-7447-19900801-06.
Many orthopedic surgeons are unfamiliar with the various types of commercially available allograft bones, despite their frequent use in reconstructive and tumor surgery. This report summarizes the mechanical, osteoinduction, and safety data for sterile fresh-frozen, secondarily sterilized, and freeze-dried bone. The orthopedic surgeon can make informed choices about bone alternatives based on the risks and benefits of each type. Data have shown that fresh-frozen sterile-collection bone is the optimal substitute for autogenous bone in most applications.
尽管同种异体移植骨在重建手术和肿瘤手术中经常使用，但许多骨科医生并不熟悉市面上各种类型的同种异体移植骨。本报告总结了无菌新鲜冷冻骨、二次灭菌骨和冻干骨的力学、骨诱导和安全性数据。骨科医生可以根据每种类型的风险和益处，对骨替代物做出明智的选择。数据表明，在大多数应用中，新鲜冷冻无菌采集骨是自体骨的最佳替代品。
