Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
Injury. 2009 Dec;40(12):1260-4. doi: 10.1016/j.injury.2009.01.116. Epub 2009 May 31.
The use of allograft bone is increasingly common in orthopaedic reconstruction procedures. The optimal method of preparation of allograft bone is subject of great debate. Proponents of fresh-frozen graft cite improved biological and biomechanical characteristics relative to irradiated material, whereas fear of bacterial or viral transmission warrants some to favour irradiated graft. Careful review of the literature is necessary to appreciate the influence of processing techniques on bone quality. Whereas limited clinical trials are available to govern the selection of appropriate bone graft, this review presents the argument favouring the use of fresh-frozen bone allograft as compared to irradiated bone.
同种异体骨在骨科重建手术中的应用越来越普遍。同种异体骨的最佳制备方法是一个备受争议的话题。新鲜冷冻移植物的支持者认为，与辐照材料相比，其具有更好的生物学和生物力学特性，而对细菌或病毒传播的担忧则使一些人赞成辐照移植物。有必要仔细审查文献，以了解处理技术对骨质量的影响。虽然有有限的临床试验来指导合适的骨移植物的选择，但本文综述了支持使用新鲜冷冻骨同种异体骨而不是辐照骨的观点。
