Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
J Dermatol. 2013 Oct;40(10):837-9. doi: 10.1111/1346-8138.12222. Epub 2013 Aug 20.
Reports of seborrheic keratosis (SK) with concurrent malignant tumors are rare, but previous and recent reports - especially the co-manifestation of basal cell carcinomas (BCC) have added to the ongoing debate of the possibility of the development of BCC from SK. We report a rare case of SK with underlying BCC with scarcely accounted histopathological characteristics - reticulated type and nodular type, respectively - that showed no direct histological link between the two entities. We also carefully suggest that differences in histopathology (whether the two lesions are connected or not) may account for the possibility of incidental co-habitation.
脂溢性角化病（SK）合并恶性肿瘤的报告较为罕见，但以往和近期的报告 - 尤其是基底细胞癌（BCC）的同时出现 - 增加了 SK 发展为 BCC 的可能性的持续争论。我们报告了一例罕见的 SK 伴发 BCC，其组织病理学特征分别为网状型和结节型，两者之间没有直接的组织学联系。我们还仔细建议，组织病理学的差异（两个病变是否相连）可能解释了偶然共存的可能性。
