Swinburne Centre for Human Psychopharmacology, Swinburne University, Hawthorn, Melbourne, Victoria, Australia.
J Pharm Pharm Sci. 2013;16(2):254-8. doi: 10.18433/j35g6m.
Bacopa monniera (EBm), an Indian aquatic herb, has been used in traditional Ayurvedic medicine for centuries for indications related to memory and inflammation. More recently specific extracts of EBm have emerged that have been subjected to rigorous in vitro, animal and now human clinical trials. In this paper we discuss some of these studies with special reference to mechanisms and efficacy of a special extract of Bacopa (CDRI08). Studies using this extract indicate that CDRI08 has several modes of action on the human brain. Promising indications for use in humans include improving cognition in the elderly and in patients with neurodegenerative disorders.
印度水生草本植物益智（EBm）在传统的印度阿育吠陀医学中已被使用了数个世纪，用于治疗与记忆和炎症相关的疾病。最近，特定的益智提取物已经经过了严格的体外、动物和现在的人体临床试验。在本文中，我们将特别参考一种特殊的益智提取物（CDRI08）的机制和疗效来讨论其中的一些研究。使用该提取物的研究表明，CDRI08 对人类大脑有多种作用方式。在人类中使用的有前途的适应症包括改善老年人和神经退行性疾病患者的认知能力。
