Mel'nichenko G A, Gitel' E P, Romantsova T I
Probl Endokrinol (Mosk). 1990 May-Jun;36(3):29-33.
The authors presented the results of catamnestic investigation of 133 women treated with bromocriptine for various types of hyperprolactinemic hypogonadism. A high effectiveness and safety of bromocriptine therapy were observed. Methods of prevention of probable complications were proposed. The authors evaluated the health status of children born to patients treated with bromocriptine. The most prolonged remissions were observed in patients with macroprolactinemia who gave birth to children owing to bromocriptine therapy. Most patients develop a relapse of the disease after therapy discontinuation and therefore need repeated therapeutic courses. In the authors' opinion, prolonged bromocriptine therapy is a serious alternative to surgery and radiotherapy.
作者展示了对133名因各种类型高催乳素血症性腺功能减退而接受溴隐亭治疗的女性进行的随访调查结果。观察到溴隐亭治疗具有高效性和安全性。提出了预防可能并发症的方法。作者评估了接受溴隐亭治疗的患者所生孩子的健康状况。在因溴隐亭治疗而生育孩子的大泌乳素血症患者中观察到最长的缓解期。大多数患者在停药后疾病复发,因此需要重复治疗疗程。作者认为,长期溴隐亭治疗是手术和放疗的一种重要替代方法。