Cordova A, Perreau C, Schmaltz-Panneau B, Locatelli Y, Ponsart C, Mermillod P
UMR7247, physiologie de la reproduction et des comportements, Institut national de recherche agronomique (INRA), 37380 Nouzilly, France.
Gynecol Obstet Fertil. 2013 Sep;41(9):537-9. doi: 10.1016/j.gyobfe.2013.07.015. Epub 2013 Aug 16.
Beyond being a pipe between ovary and uterus, the oviduct is an active player in different aspects of early reproductive processes, in particular in the transport of embryos to the site of implantation and the regulation of its early development. Different studies evidenced a communication between oviduct and early embryo at the molecular and functional levels. Since the study of these interactions is difficult in vivo, different in vitro systems have been developed to mimic the maternal milieu during early development. These systems allowed to confirm the action of the cells on the quality of early development (blastocyst rate and viability). In turn, the embryos are producing signals that are able to modify and adapt the activity of maternal cells.
输卵管不仅是卵巢与子宫之间的管道,还是早期生殖过程不同方面的积极参与者,特别是在将胚胎运输到着床部位以及调节其早期发育方面。不同的研究证明了输卵管与早期胚胎在分子和功能水平上的交流。由于在体内研究这些相互作用很困难,因此已经开发了不同的体外系统来模拟早期发育过程中的母体环境。这些系统能够证实细胞对早期发育质量(囊胚率和活力)的作用。反过来,胚胎也在产生能够改变和调节母体细胞活性的信号。