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迈向口腔癌虚拟手术以术前预测术后口腔功能。

Towards virtual surgery in oral cancer to predict postoperative oral functions preoperatively.

作者信息

van Alphen M J A, Kreeft A M, van der Heijden F, Smeele L E, Balm A J M

机构信息

Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands; MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, The Netherlands.

出版信息

Br J Oral Maxillofac Surg. 2013 Dec;51(8):747-51. doi: 10.1016/j.bjoms.2013.06.012. Epub 2013 Aug 16.

DOI:10.1016/j.bjoms.2013.06.012
PMID:23958349
Abstract

Our aim was to develop a dynamic virtual model of the oral cavity and oropharynx so that we could incorporate patient-specific factors into the prediction of functional loss after advanced resections for oral cancer. After a virtual resection, functional consequences can be assessed, and a more substantiated decision about treatment can be made. In this study we used a finite element model of the tongue, which can be implemented in the total virtual environment in the future. We analysed the movements and changes in volume, and the effects of changes in the material variables, to mimic scar tissue. The observed movements were in accordance with descriptions of in vivo movements. Affected movements caused by the mimicked scar tissue were also similar to expectations. Some changes in volume were measured, particularly in individual elements. We have taken the first steps in the development of a finite element model of the tongue. Now, refinement is necessary to make the model suitable for future use in virtual surgery.

摘要

我们的目标是开发一个口腔和口咽的动态虚拟模型,以便我们能够将患者的特定因素纳入口腔癌晚期切除术后功能丧失的预测中。在进行虚拟切除后,可以评估功能后果,并做出更有依据的治疗决策。在本研究中,我们使用了一个舌头的有限元模型,该模型未来可在整个虚拟环境中实现。我们分析了舌头的运动、体积变化以及模拟瘢痕组织时材料变量变化的影响。观察到的运动与体内运动的描述一致。由模拟瘢痕组织引起的受影响运动也与预期相似。我们测量到了一些体积变化,特别是在单个单元中。我们已经在舌头有限元模型的开发方面迈出了第一步。现在,有必要对模型进行优化,使其适合未来在虚拟手术中的应用。

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