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达金溶液:过去、现在和未来。

Dakin's solution: past, present, and future.

机构信息

Center for Advanced Wound Care, Beth Israel Medical Center, Albert Einstein College of Medicine, New York, New York, USA.

出版信息

Adv Skin Wound Care. 2013 Sep;26(9):410-4. doi: 10.1097/01.ASW.0000432051.59348.cd.

DOI:10.1097/01.ASW.0000432051.59348.cd
PMID:23958873
Abstract

Dakin's solution has been used for almost a century. It is a dilute solution of sodium hypochlorite, which is commonly known as household bleach. When properly applied, it can kill pathogenic microorganisms with minimum cytotoxicity. This article reviews its history and discusses how evolving technology might pave the way for a new role for this antiseptic.

摘要

达金溶液已经使用了近一个世纪。它是一种稀 释的次氯酸钠溶液,通常称为家用漂白剂。当正确使用时,它可以在最小细胞毒性的情况下杀死致病微生物。本文回顾了它的历史,并讨论了不断发展的技术如何为这种防腐剂开辟新的角色。

相似文献

1
Dakin's solution: past, present, and future.达金溶液:过去、现在和未来。
Adv Skin Wound Care. 2013 Sep;26(9):410-4. doi: 10.1097/01.ASW.0000432051.59348.cd.
2
Dakin's solution: historical perspective and current practice.达金氏溶液:历史回顾与当前应用
Ann Plast Surg. 2014 Sep;73(3):254-6. doi: 10.1097/SAP.0b013e3182a634f7.
3
Historical review of Dakin's solution applications.达金氏溶液应用的历史回顾。
J Plast Reconstr Aesthet Surg. 2018 Sep;71(9):e49-e55. doi: 10.1016/j.bjps.2018.05.023. Epub 2018 Jun 8.
4
Dakin's Solution: "One of the most important and far-reaching contributions to the armamentarium of the surgeons".达金氏溶液:“外科医生武器库中最重要、最具深远意义的贡献之一”。
Burns. 2019 Nov;45(7):1509-1517. doi: 10.1016/j.burns.2018.12.001. Epub 2018 Dec 24.
5
Dakin's solution revisited.重温达金氏溶液。
Am J Orthop (Belle Mead NJ). 1997 Jul;26(7):471-3.
6
Tissue-dissolving capacity and antibacterial effect of buffered and unbuffered hypochlorite solutions.缓冲和未缓冲次氯酸盐溶液的组织溶解能力及抗菌效果。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 Dec;94(6):756-62. doi: 10.1067/moe.2002.128961.
7
Effect of Dakin's solution on components of a dermal equivalent.达金氏溶液对皮肤替代物成分的影响。
J Surg Res. 2009 Jul;155(1):54-64. doi: 10.1016/j.jss.2008.08.007. Epub 2008 Sep 8.
8
Our historical roots: Dr Richard Drysdale Dakin, DSc, and his solution.我们的历史渊源:理查德·德赖斯代尔·达金博士,理学博士,以及他的溶液。
J Wound Ostomy Continence Nurs. 2008 May-Jun;35(3):289-92. doi: 10.1097/01.WON.0000319127.98983.2c.
9
Sodium hypochlorite: history, properties, electrochemical production.次氯酸钠:历史、性质、电化学生产
Contrib Nephrol. 2007;154:7-23. doi: 10.1159/000096810.
10
Rapid degradation and non-selectivity of Dakin's solution prevents effectiveness in contaminated musculoskeletal wound models.达金氏溶液的快速降解和非选择性使其在受污染的肌肉骨骼创伤模型中无法发挥有效作用。
Injury. 2018 Oct;49(10):1763-1773. doi: 10.1016/j.injury.2018.08.004. Epub 2018 Aug 6.

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Comparing the in Vitro Efficacy of Commonly Used Surgical Irrigants for the Treatment of Implant-Associated Infections.比较常用外科冲洗液治疗植入物相关感染的体外疗效。
J Bone Joint Surg Am. 2025 Jun 19;107(16):1818-1824. doi: 10.2106/JBJS.24.01225.
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Effects of hypochlorous acid mouthwash on salivary bacteria including Staphylococcus aureus in patients with periodontal disease: a randomized controlled trial.次氯酸含漱液对牙周病患者唾液细菌(包括金黄色葡萄球菌)的影响:一项随机对照试验。
BMC Oral Health. 2023 Sep 28;23(1):698. doi: 10.1186/s12903-023-03358-4.
3
The Continued Utility and Viability of Dakin's Solution in Both High- and Low-resource Settings.
达金氏溶液在高资源和低资源环境中的持续效用与可行性
Arch Bone Jt Surg. 2020 Mar;8(2):198-203. doi: 10.22038/abjs.2019.34372.1906.
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Instillation negative pressure wound therapy: An effective approach for hardware salvage.灌注式负压伤口疗法:一种有效的硬件保留方法。
Int Wound J. 2020 Apr;17(2):387-393. doi: 10.1111/iwj.13283. Epub 2019 Dec 19.
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Honey-Based Salve and Burdock Leaf Dressings as an Alternative to Surgical Debridement of a Traumatic Wound Eschar.蜂蜜基药膏和牛蒡叶敷料作为创伤性伤口焦痂手术清创的替代方法。
Adv Wound Care (New Rochelle). 2019 Mar 1;8(3):101-107. doi: 10.1089/wound.2018.0806. Epub 2019 Mar 5.
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Retroperitoneal Necrotizing Fasciitis from Fournier's Gangrene in an Immunocompromised Patient.免疫功能低下患者发生的源于福尼尔坏疽的腹膜后坏死性筋膜炎。
Case Rep Surg. 2017;2017:5290793. doi: 10.1155/2017/5290793. Epub 2017 Dec 3.
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Dakin's solution: is there a place for it in the 21st century?达金溶液:在 21 世纪它还有一席之地吗?
Int Wound J. 2017 Dec;14(6):918-920. doi: 10.1111/iwj.12728. Epub 2017 Feb 15.