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作为盐酸普萘洛尔缓释剂型的流体动力学平衡系统

Hydrodynamically balanced systems as sustained release dosage forms for propranolol hydrochloride.

作者信息

Khattar D, Ahuja A, Khar R K

机构信息

Department of Pharmaceutics, Hamdard College of Pharmacy, New Dehli, India.

出版信息

Pharmazie. 1990 May;45(5):356-8.

PMID:2395898
Abstract

Sustained release hydrodynamically balanced capsules (HBS) of propranolol.HCl have been prepared and evaluated in vitro. Data to support the mechanism of drug release from the HBS capsule are also presented. Floating behaviour of the HBS capsule has also been seen in vivo with the help of endoscopy.

摘要

已制备盐酸普萘洛尔的缓释流体动力学平衡胶囊（HBS）并进行体外评价。还给出了支持药物从HBS胶囊释放机制的数据。借助内窥镜检查，在体内也观察到了HBS胶囊的漂浮行为。

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