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喝茶时加牛奶会延缓胃排空吗?

Does adding milk to tea delay gastric emptying?

机构信息

Department of Anaesthesia, Rockingham General Hospital, Elanora Drive, Rockingham, WA 6168, Australia.

出版信息

Br J Anaesth. 2014 Jan;112(1):66-71. doi: 10.1093/bja/aet261. Epub 2013 Aug 19.

Abstract

BACKGROUND

Many preoperative fasting guidelines suggest that hot tea or coffee with milk added should be considered similar to solid food, allowing an interval of 6 h before commencing anaesthesia. There is little evidence to support these instructions, with recent guidelines undecided on the issue. This study aimed to establish whether there was a clinically significant delay in gastric emptying associated with adding a modest amount of milk to tea.

METHODS

This randomized controlled crossover study was conducted in 10 healthy volunteers. The paracetamol absorption technique and real-time ultrasound measurement of the cross-sectional area of the gastric antrum were used to assess gastric emptying after ingestion of 300 ml of black tea or 300 ml of tea with milk (250 ml black tea plus 50 ml of full fat milk).

RESULTS

The mean difference in the time to reach the peak paracetamol concentration (tmax) was -8 min [95% confidence interval (CI) -23.1 to 7] in favour of tea with milk. Ultrasound assessment indicated that the geometric mean of the half-time to gastric emptying (T₁/₂) after tea without milk was 22.7 (95% CI 12.7-40.9) min and after tea with milk 23.6 (95% CI 13.5-41.0) min (ratio 1.04) (95% CI 0.47-2.29).

CONCLUSIONS

This study demonstrated no difference in gastric emptying times when a modest amount of milk was added to tea. These findings suggest that it may be acceptable to allow patients to add a small quantity of milk to their tea or coffee and follow the same fasting restrictions applied to clear fluids.

摘要

背景

许多术前禁食指南建议,应将加奶的热茶或咖啡视为固体食物,在开始麻醉前需禁食 6 小时。这些指导原则缺乏证据支持,最近的指南也未对此问题作出明确规定。本研究旨在确定在茶中加入少量牛奶是否会导致胃排空明显延迟。

方法

这是一项在 10 名健康志愿者中进行的随机对照交叉研究。采用对乙酰氨基酚吸收技术和实时超声测量胃窦横截面积来评估饮用 300ml 红茶或加奶茶(250ml 红茶加 50ml 全脂牛奶)后胃排空情况。

结果

与加奶茶相比,达峰时间(tmax)的平均差值为-8 分钟(95%置信区间-23.1 至 7),有利于加奶茶。超声评估结果表明,无奶茶的胃排空半时(T₁/₂)几何平均值为 22.7(95%置信区间 12.7-40.9)分钟,加奶茶为 23.6(95%置信区间 13.5-41.0)分钟(比值 1.04)(95%置信区间 0.47-2.29)。

结论

本研究表明,在茶中加入少量牛奶不会导致胃排空时间差异。这些发现表明,允许患者在茶或咖啡中加入少量牛奶,并遵循与清水相同的禁食限制,可能是可以接受的。

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