Nooh Nasser
Department of Oral and Maxillofacial Surgery, College of Dentistry, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia.
Saudi Dent J. 2009 Jul;21(2):57-61. doi: 10.1016/j.sdentj.2009.07.001. Epub 2009 Aug 5.
Acetylsalicylic acid (ASA) generically known as aspirin is used clinically as an analgesic, antipyretic, anti-inflammatory and as a medication to prevent platelet aggregation. Many studies have investigated bleeding associated with ASA.
The aim of this study was to determine if ASA was associated with bleeding after dental extraction.
One hundred and eighty-nine subjects were divided into four groups. Group 1A subjects who received ASA, underwent simple extraction. Group 1B subjects who received ASA, underwent surgical extraction. Group 2A subjects who did not receive ASA, underwent simple extraction which served as control group. Group 2B subjects who did not receive ASA, underwent surgical extraction which also served as control group.
The results showed that Group 1B was the only group which showed bleeding after 24 h. All groups had similar results after 48 h and 5 days post-operatively.
The study concluded that subjects who received 81 mg ASA daily could undergo dental extraction without bleeding risks.
乙酰水杨酸(ASA)通常被称为阿司匹林,在临床上用作镇痛药、退烧药、抗炎药以及预防血小板聚集的药物。许多研究都调查了与ASA相关的出血情况。
本研究的目的是确定ASA是否与拔牙后出血有关。
189名受试者被分为四组。1A组受试者接受ASA并进行简单拔牙。1B组受试者接受ASA并进行外科拔牙。2A组受试者未接受ASA,进行简单拔牙作为对照组。2B组受试者未接受ASA,进行外科拔牙也作为对照组。
结果显示,1B组是唯一在24小时后出现出血的组。术后48小时和5天时,所有组的结果相似。
该研究得出结论,每天服用81毫克ASA的受试者可以进行拔牙,而没有出血风险。