二氢嘧啶衍生物的合成、表征及生物评价。
Synthesis, characterization and biological evaluation of dihydropyrimidine derivatives.
机构信息
Department of Studies in Chemistry, Mangalore University, Mangalagangothri 574 199, Karnataka, India.
出版信息
Saudi Pharm J. 2012 Jan;20(1):75-9. doi: 10.1016/j.jsps.2011.04.002. Epub 2011 Apr 23.
Abstract
A series of dihydropyrimidines containing quinoline were prepared under conventional heating and microwave irradiation. The structures of newly synthesized compounds were established based on analytical and spectral studies. Further these compounds were evaluated for their antioxidant, antifungal and antibacterial activities. Most of the compounds showed moderate to good activity when compared with standard.
摘要
一系列含喹啉的二氢嘧啶在常规加热和微波辐射下制备而成。根据分析和光谱研究确定了新合成化合物的结构。进一步评估了这些化合物的抗氧化、抗真菌和抗菌活性。与标准品相比，大多数化合物表现出中等至良好的活性。
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