Mokbel Tahrwat H, Ghanem Asaad A, Moawad Ashraf I, Nafie Ehab M, Nematallah Ehab H
Ophthalmology Center, Faculty of Medicine, Mansoura University, Egypt.
Saudi J Ophthalmol. 2009 Oct;23(3-4):189-96. doi: 10.1016/j.sjopt.2009.10.008. Epub 2009 Oct 28.
To compare the surgical outcomes of phacoemulsification-subscleral trabeculectomy versus phacoemulsification-deep sclerectomy with intraoperative mitomycin C in open-angle glaucoma.
The study was conducted on 40 chronic primary open-angle glaucomatous eyes with senile cataract. They were divided into two groups: group I (n = 20): eyes undergoing phacoemulsification with subscleral trabeculectomy, and group II (n = 20): eyes undergoing phacoemulsification with deep sclerectomy. Intraoperative mitomycin C (0.4 mg/ml for 3 min) was applied in both groups. Postoperative intraocular pressure (IOP), complications, glaucoma medications, visual outcomes, and the bleb appearance were assessed for 12 months.
The mean postoperative IOP was significantly lower (P < 0.05) in both groups in all time intervals in comparison to their preoperative values. The mean postoperative IOP was 14.1 ± 5.4 mmHg in group I, and 14.8 ± 3.1 mmHg in group II. No major complications were encountered in either procedure, but complications such as shallow anterior chamber, hypotony, and delayed bleb leaks were common in group I, whereas intraoperative perforation of Descemet's membrane occurred in group II. No significant difference in visual acuity improvement, visual field changes, and surgical success outcome were found between both groups.
There was no significant difference in IOP reduction, surgical complications and visual outcomes between subscleral trabeculectomy, or deep sclerectomy with intraoperative mitomycin C in combination with phacoemulsification and intraocular lens implantations in patients with primary open-angle glaucoma.
比较超声乳化巩膜下小梁切除术与超声乳化深层巩膜切除术联合术中丝裂霉素C治疗开角型青光眼的手术效果。
对40只患有老年性白内障的慢性原发性开角型青光眼患眼进行研究。将其分为两组:第一组(n = 20):接受超声乳化巩膜下小梁切除术的患眼;第二组(n = 20):接受超声乳化深层巩膜切除术的患眼。两组均术中应用丝裂霉素C(0.4mg/ml,持续3分钟)。对术后12个月的眼压、并发症、青光眼用药情况、视力结果及滤过泡外观进行评估。
与术前值相比,两组在所有时间间隔的术后平均眼压均显著降低(P < 0.05)。第一组术后平均眼压为14.1±5.4mmHg,第二组为14.8±3.1mmHg。两种手术均未出现严重并发症,但第一组常见浅前房、低眼压和延迟性滤过泡渗漏等并发症,而第二组发生了术中Descemet膜穿孔。两组在视力改善、视野变化及手术成功率方面未发现显著差异。
对于原发性开角型青光眼患者,超声乳化联合人工晶状体植入术中,巩膜下小梁切除术或深层巩膜切除术联合术中丝裂霉素C在眼压降低、手术并发症及视力结果方面无显著差异。