Al-Muammar Abdulrahman
Department of Ophthalmology, College of Medicine, King Saud University, King Abdulaziz University Hospital, Airport Road, P.O. Box 245, Riyadh 11411, Saudi Arabia.
Saudi J Ophthalmol. 2011 Jul;25(3):305-8. doi: 10.1016/j.sjopt.2011.03.001. Epub 2011 Mar 15.
This is a report of two brothers who underwent bilateral photorefractive keratectomy and developed bilateral peripheral corneal infiltrate on the third day following surgery. The patients were treated with antibiotics and low concentration steroid until negative culture was reported 48 h later, when intensive topical steroid was started. The infiltrate resolved by day 10 with residual subepithelial haze that was apparent 8 months after surgery. Sterile infiltrate has been reported as complication of photorefractive keratectomy and can be managed successfully with excellent outcome. The fact that it happened in two brothers may raise the possibility of genetic predisposition.
本文报告了两兄弟接受双侧准分子激光原位角膜磨镶术（PRK）后，在术后第三天出现双侧周边角膜浸润的病例。患者接受了抗生素和低浓度类固醇治疗，直至48小时后培养结果为阴性，随后开始使用强化局部类固醇治疗。浸润在第10天时消退，术后8个月仍有残留的上皮下混浊。无菌性浸润已被报道为准分子激光原位角膜磨镶术的并发症，通过成功治疗可获得良好预后。该情况发生在两兄弟身上这一事实可能提示存在遗传易感性。
