Consultant Ophthalmologist, Cataract and Refractive Surgery Services, LV Prasad Eye Institute, Hyderabad, Telangana, India.
Fellow Ophthalmologist, Cataract and Refractive Surgery Services, LV Prasad Eye Institute, Hyderabad, Telangana, India.
Indian J Ophthalmol. 2020 Dec;68(12):2956-2959. doi: 10.4103/ijo.IJO_1300_20.
Sterile infiltrates following laser refractive surgery is an uncommon complication. This study was undertaken to analyze the visual outcomes of sterile infiltrates following photorefractive keratectomy (PRK).
This retrospective study included 14 eyes that developed sterile infiltrates following PRK out of a total of 6280 eyes that underwent PRK between 2014 and 2017. Medical records of these patients, including patient demographics, characteristics of the infiltrate, presenting visual acuity, and treatment outcomes were recorded and analyzed.
The incidence of sterile corneal infiltrates post-PRK in our study was 0.22% (14/6280). The mean age of the patients was 27.42 ± 4.87 years. The uncorrected visual acuity (UCVA) at presentation was 0.49 ± 0.13 log MAR units. The mean size of the infiltrate was 3.22 ± 2.85 mm. All cases were successfully managed medically with topical steroids. The mean UCVA and best-corrected visual acuity (BCVA) at the last follow-up visit were 0.08 ± 0.08 and 0.05 ± 0.07 log MAR units, respectively. The mean time taken for resolution of the infiltrate was 8.91 ± 4.57 days.
Sterile infiltrates following PRK can be effectively treated with aggressive topical steroids. The outcome is generally favorable and does not require surgical intervention if treatment is instituted early.
激光屈光手术后出现无菌性浸润是一种罕见的并发症。本研究旨在分析准分子激光角膜切削术(PRK)后无菌性浸润的视力结果。
本回顾性研究纳入了 2014 年至 2017 年间行 PRK 治疗的 6280 只眼中出现 14 只(0.22%)无菌性角膜浸润的患者。记录并分析了这些患者的病历,包括患者人口统计学资料、浸润特征、就诊时的视力和治疗结果。
本研究中 PRK 后无菌性角膜浸润的发生率为 0.22%(14/6280)。患者的平均年龄为 27.42±4.87 岁。就诊时的未矫正视力(UCVA)为 0.49±0.13 logMAR 单位。浸润的平均大小为 3.22±2.85mm。所有病例均经局部皮质类固醇成功治疗。末次随访时的平均 UCVA 和最佳矫正视力(BCVA)分别为 0.08±0.08 和 0.05±0.07 logMAR 单位。浸润消退的平均时间为 8.91±4.57 天。
PRK 后无菌性浸润可通过积极的局部皮质类固醇治疗有效治疗。如果早期治疗,结果通常是有利的,不需要手术干预。