Alotaibi Abdullah G, Al Enazi Badriah
Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Saudi J Ophthalmol. 2011 Oct;25(4):405-9. doi: 10.1016/j.sjopt.2011.06.001. Epub 2011 Jul 16.
This study was performed to measure the macular and the retinal nerve fiber layer (RNFL) thicknesses using optical coherence tomography (OCT) in patients with unilateral amblyopia.
Measurement of the Retinal nerve fiber layer and Macular Retinal Layer thickness for both amblyopic and normal fellow eyes by (OCT) was carried out at king Abdulaziz University Hospital, Riyadh, Saudi Arabia.
Ninety-three patients with unilateral amblyopia between the ages of 5 years and 12 years were included. The macular retinal thickness and the RNFL thickness were measured using OCT. The mean macular retinal thickness was 259.3 μm and 255.6 μm, and the mean RNFL thickness was 112.16 μm and 106 μm, in the amblyopic eye and the normal eye, respectively. OCT assessment of RNFL thickness revealed a significantly thicker RNFL in amblyopic eye (P < 0.0001), but no statistically significant difference was found in macular retinal thickness (P = 0.195).
The amblyopic process may involve the RNFL, but not the macula. However, further evaluation is needed.
本研究旨在使用光学相干断层扫描（OCT）测量单侧弱视患者的黄斑和视网膜神经纤维层（RNFL）厚度。
在沙特阿拉伯利雅得的阿卜杜勒阿齐兹国王大学医院，通过OCT对弱视眼和正常对侧眼的视网膜神经纤维层和黄斑视网膜层厚度进行测量。
纳入了93例年龄在5岁至12岁之间的单侧弱视患者。使用OCT测量黄斑视网膜厚度和RNFL厚度。弱视眼和正常眼的平均黄斑视网膜厚度分别为259.3μm和255.6μm，平均RNFL厚度分别为112.16μm和106μm。OCT对RNFL厚度的评估显示弱视眼的RNFL明显更厚（P < 0.0001），但黄斑视网膜厚度无统计学显著差异（P = 0.195）。
弱视过程可能涉及RNFL，但不涉及黄斑。然而，需要进一步评估。
