Albreiki Danah H, Gilberg Steven M, Farmer James P
University of Ottawa Eye Institute, Ottawa, ON, Canada.
Saudi J Ophthalmol. 2012 Apr;26(2):151-6. doi: 10.1016/j.sjopt.2012.02.006.
Malignant melanoma of the conjunctiva is a relatively infrequent neoplasm that can be associated with significant morbidity and cause diagnostic difficulty to both the ophthalmologist and pathologist. We herein describe the first reported case in North American and European databases of a rare variant-signet ring cell melanoma - arising in the background of primary acquired melanosis (PAM) and use this case as a review of important diagnostic and therapeutic considerations when faced with this condition.
结膜恶性黑色素瘤是一种相对罕见的肿瘤，可伴有严重的发病率，给眼科医生和病理学家的诊断带来困难。我们在此描述北美和欧洲数据库中首次报告的一例罕见变异型——印戒细胞黑色素瘤，它发生于原发性获得性黑色素沉着（PAM）背景下，并以此病例回顾面对这种情况时重要的诊断和治疗考量。
