视网膜母细胞瘤重大综述及中东地区管理方案的更新
Retinoblastoma major review with updates on Middle East management protocols.
作者信息
Othman Ihab Saad
机构信息
National Eye Center, Rod El-Farag, Cairo, Egypt.
出版信息
Saudi J Ophthalmol. 2012 Apr;26(2):163-75. doi: 10.1016/j.sjopt.2012.03.002.
Abstract
Many advances in the field of management of retinoblastoma emerged in the past few years. Patterns of presentation of retinoblastoma in the Middle East region differ from Western community. The use of enucleation as a radical method of eradicating advanced disease is not easily accepted by patient's family. We still do see stage E, failed or resistant retinoblastoma and advanced extraocular disease ensues as a result of delayed enucleation decision. In this review, we discuss updates in management of retinoblastoma with its implication on patients in our part of the world. Identifying clinical and high risk characteristics is important prognostically and are discussed for further management of retinoblastoma cases.
摘要
过去几年里，视网膜母细胞瘤管理领域取得了许多进展。中东地区视网膜母细胞瘤的表现形式与西方群体有所不同。作为根除晚期疾病的一种根治性方法，眼球摘除术不易被患者家属接受。我们仍会看到E期、治疗失败或耐药的视网膜母细胞瘤，因眼球摘除术决策延迟而导致晚期眼外疾病。在这篇综述中，我们讨论视网膜母细胞瘤管理方面的最新进展及其对我们所在地区患者的影响。识别临床和高危特征在预后方面很重要，并针对视网膜母细胞瘤病例的进一步管理进行了讨论。
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