眼眶弥漫性大B细胞淋巴瘤：沙特阿拉伯一家三级眼科护理中心的经验。
Diffuse large B-cell lymphoma of the orbit: A tertiary eye care center experience in Saudi Arabia.
作者信息
Alkatan Hind M, Alaraj Ahmad M, Al-Ayoubi Ayman
机构信息
Pathology and Laboratory Medicine department, King Khaled Eye Specialist Hospital, P.O. Box 7191, Riyadh 11462, Saudi Arabia.
出版信息
Saudi J Ophthalmol. 2012 Apr;26(2):235-9. doi: 10.1016/j.sjopt.2011.09.004. Epub 2011 Dec 28.
Primary Diffuse Large B-cell Lymphoma (DLBCL) represents the 2nd most common lymphoma occurring in the orbit, after Mucosal Associated Lymphoid Tissue (MALT) lymphoma. A total of 5 cases of ocular adnexal DLBCL were diagnosed over 25 years of experience at our tertiary eye care center. Two cases involved the lacrimal sac and one case involved the lacrimal gland. In this paper we are presenting the remaining 2 non-lacrimal cases of DLBCL. The first case is a 32 year old male who was referred with a slowly growing, painless mass involving the left medial canthal area as a case of dacryocystitis. The mass was found to be extending into the orbit inferiorly with upward displacement of the left globe. The second case is a 65 year-old lady who presented with unilateral proptosis as a result of a right orbital mass extending to the orbital apex. Histopathologic examination and immunohistochemical analysis of the incisional biopsy in both cases confirmed the diagnosis of Diffuse Large B-cell Lymphoma (DLBCL).
原发性弥漫性大B细胞淋巴瘤（DLBCL）是眼眶中第二常见的淋巴瘤，仅次于黏膜相关淋巴组织（MALT）淋巴瘤。在我们的三级眼科护理中心25年的经验中，共诊断出5例眼附属器DLBCL。2例累及泪囊，1例累及泪腺。在本文中，我们将呈现其余2例非泪腺部位的DLBCL病例。第一例是一名32岁男性，因左侧内眦部缓慢生长、无痛性肿块被转诊，初诊为泪囊炎。发现肿块向下延伸至眼眶，导致左眼球向上移位。第二例是一名65岁女性，因右侧眼眶肿块延伸至眶尖导致单侧眼球突出。两例病例的切开活检组织病理学检查和免疫组化分析均确诊为弥漫性大B细胞淋巴瘤（DLBCL）。
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